George Kuo

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George Ching-Hung Kuo is a Taiwanese -US virologist . Kuo discovered the hepatitis C virus in 1989 together with Qui-Lim Choo , Michael Houghton and Daniel W. Bradley .

Life

Kuo graduated from Taiwan National University in 1961 and received his PhD in molecular biology from Albert Einstein College of Medicine , New York City, in 1972 . From 1981 he worked for the Chiron Corporation . It had been known since the 1970s that many cases of infectious hepatitis were not caused by the two viruses known at the time, hepatitis A virus and hepatitis B virus . From 1982 onwards, a research group led by Michael Houghton at Chiron, in which Kuo was also involved, concentrated on the search for the pathogen causing "Non-A-Non-B (NANB) hepatitis". After years of work in 1989, the research group was able to isolate a short piece of nucleic acid from the plasma of chimpanzees with NANB hepatitis, which turned out to be part of a previously unknown virus. This was later called the "hepatitis C virus".

Kuo is married to his colleague Carol Lan-Fang Kuo; his daughter Irene Carol Kuo is an Associate Professor of Ophthalmology at The Johns Hopkins Wilmer Eye Institute .

Awards

Individual evidence

  1. a b WEDDINGS / CELEBRATIONS; Irene Kuo, Carson Chow. In: nytimes.com (April 24, 2005).
  2. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M: Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome . In: Science . 244, No. 4902, April 1989, pp. 359-62. doi : 10.1126 / science.2523562 . PMID 2523562 .
  3. Liver Cirrhosis and Its Development - Google Books . books.google.co.uk, (Retrieved October 5, 2016).
  4. Michael Houghton: The long and winding road leading to the identification of the hepatitis C virus. Journal of Hepatology 2009; 51 (5): 939-948 doi : 10.1016 / j.jhep.2009.08.004
  5. Michael Houghton: The hepatitis C virus: A new paradigm for the identification and control of infectious disease. Nature Medicine 2000: 6 (10): 1984-86 pdf