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Structural formula
Structure of witchcraft
Surname Witchcraft
other names

2 ′, 5′-di- O -galloyl- D -hamamelose

Molecular formula C 20 H 20 O 14
Brief description

white solid

External identifiers / databases
CAS number 469-32-9
EC number 207-416-3
ECHA InfoCard 100.006.744
PubChem 44584241
ChemSpider 21468878
Wikidata Q15632711
Molar mass 484.36 g mol −1
Physical state



1.93 g cm −3

Melting point

130-145 ° C

  • almost insoluble in water
  • soluble in methanol, acetone and dioxane
safety instructions
GHS labeling of hazardous substances
no GHS pictograms
H and P phrases H: no H-phrases
P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Hamamelitannin is a natural substance of the Virginian witch hazel ( Hamamelis virginiana ) and belongs to the gallotannins .

Virginian witch hazel ( Hamamelis virginiana )


Hamamelitannin significantly reduces the metabolic activity of biofilms with the bacteria Staphylococcus epidermidis , Staphylococcus aureus , Acinetobacter baumannii and Candida albicans . It shows specific cytotoxic activity against colon cancer cells.

Individual evidence

  1. a b c d Datasheet Hamamelitannin at Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).
  2. a b c d Datasheet Hamamelitannin at Santa Cruz Biotech.
  3. R. Hegnauer: Chemotaxonomy of Plants: Volume 4: Dicotyledoneae: Daphniphyllaceae bis ... Springer DE, 1966, ISBN 3-7643-0167-8 , p. 242 ( limited preview in Google Book search).