Witchcraft

Structural formula
General
Surname	Witchcraft
other names	2 ′, 5′-di- O -galloyl- D -hamamelose
Molecular formula	C 20 H 20 O 14
Brief description	white solid
External identifiers / databases
CAS number 469-32-9 EC number 207-416-3 ECHA InfoCard 100.006.744 PubChem 44584241 ChemSpider 21468878 Wikidata Q15632711
properties
Molar mass	484.36 g mol −1
Physical state	firmly
density	1.93 g cm −3
Melting point	130-145 ° C
solubility	almost insoluble in water soluble in methanol, acetone and dioxane
safety instructions
GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Hamamelitannin is a natural substance of the Virginian witch hazel ( Hamamelis virginiana ) and belongs to the gallotannins .

Virginian witch hazel ( Hamamelis virginiana )

use

Hamamelitannin significantly reduces the metabolic activity of biofilms with the bacteria Staphylococcus epidermidis , Staphylococcus aureus , Acinetobacter baumannii and Candida albicans . It shows specific cytotoxic activity against colon cancer cells.

Individual evidence

1. ↑ ^{a b c d} Datasheet Hamamelitannin at Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).
2. ↑ ^{a b c d} Datasheet Hamamelitannin at Santa Cruz Biotech.
3. ↑ R. Hegnauer: Chemotaxonomy of Plants: Volume 4: Dicotyledoneae: Daphniphyllaceae bis ... Springer DE, 1966, ISBN 3-7643-0167-8 , p. 242 ( limited preview in Google Book search).