Harold Jeghers

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Harold Joseph Jeghers (born September 26, 1904 in Jersey City , † September 21, 1990 ) was an American internist . He identified the later for him and January Peutz called Peutz-Jeghers syndrome , an autosomal dominant inherited polyposis with hyperpigmentation of the lip and oral mucosa.

Life

Jeghers earned a bachelor's degree in biology from Rensselaer Polytechnic Institute in 1928 and a medical degree from Western Reserve University's medical school in Cleveland in 1932 . From 1933 he worked in various hospitals in Boston , from 1935 he also took on teaching activities at the Medical School of Boston University . Jeghers moved to Georgetown University in Washington, DC, as professor and clinical director in 1946 and to the Seton Hall College of Medicine and Dentistry (later The New Jersey College of Medicine and Dentistry ) in 1956 , where he retired in 1966. He then worked until 1974 as a professor at Tufts University and until 1978 as medical director of the St. Vincent Hospital in Worchester . During his career he also held other teaching positions, academic positions and management positions in various hospitals.

Jeghers was married to Isabel Jean Wile and had four children.

Act

The first description of the polyposis with hyperpigmentation of the lip and mouth mucosa, later called Peutz-Jeghers syndrome , was published by Jan Peutz in 1921. In a review article in 1949, Harold Jeghers, together with Victor McKusick and Kermit Katz, described ten further cases in different families and postulated an autosomal dominant inheritance . The term “Peutz-Jeghers Syndrome” was introduced in 1954 by Bruwer.

In the 1930s, Harold Jeghers began building a bibliography of medical publications that received over a million entries. After Jeghers death, the holdings of the Jeghers Medical Index (JMI) were partially digitized. The collection is held at the St. Elizabeth Health Center in Youngstown , Ohio.

Fonts (selection)

literature

  • JJ Keller, GJ Offerhaus, FM Giardiello, FH Menko: Jan Peutz, Harold Jeghers and a remarkable combination of polyposis and pigmentation of the skin and mucous membranes. In: Familial cancer. Volume 1, Number 3-4, 2001, pp. 181-185, ISSN  1389-9600 . PMID 14574176 .

Web links

Individual evidence

  1. ↑ Harold Jeghers in the US Social Security Death Directory (SSDI), accessed October 3, 2018
  2. ↑ a b Jeghers Medical Index: Curriculum Vitae: Harold Joseph Jeghers, MD ( Memento of the original from April 2, 2015 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. (PDF; 29 kB), accessed on June 15, 2013. @1@ 2Template: Webachiv / IABot / www.jeghers.com
  3. ↑ H. Jeghers, VA McKusick, KH Katz: Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits; a syndrome of diagnostic significance. In: The New England Journal of Medicine . Volume 241, Number 26, December 1949, pp. 1031-1036, ISSN  0028-4793 . doi : 10.1056 / NEJM194912292412601 . PMID 15398245 . ( Full text ( Memento of the original November 30, 2016 Internet Archive ) Info: The archive link is automatically inserted and not yet tested Please review the original and archive link under. Instructions and then remove this notice. PDF; 1.6 MB) @1@ 2Template: Webachiv / IABot / www.jeghers.com
  4. ↑ Keller et al., P. 182.
  5. ↑ a b M. Kopacova, I. Tacheci, S. Rejchrt, J. Bures: Peutz-Jeghers syndrome: diagnostic and therapeutic approach. In: World journal of gastroenterology: WJG. Volume 15, Number 43, November 2009, pp. 5397-5408, ISSN  1007-9327 . PMID 19916169 . PMC 2778095 (free full text).
  6. ^ A. Bruwer, JA Bargen, RR Kierland: Surface pigmentation and generalized intestinal polyposis; (Peutz-Jeghers syndrome). In: Proceedings of the staff meetings. Mayo Clinic. Volume 29, Number 6, March 1954, pp. 168-171, ISSN  0092-699X . PMID 13145642 .
  7. ↑ Lori M. Gawdyda: Jeghers Medical Index - History ( Memento of the original from June 17, 2013 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. . jeghers.com, accessed June 15, 2013.  @1@ 2Template: Webachiv / IABot / www.jeghers.com
personal data
SURNAME Jeghers, Harold
ALTERNATIVE NAMES Jeghers, Harold Joseph (full name)
BRIEF DESCRIPTION American internist
DATE OF BIRTH September 26, 1904
PLACE OF BIRTH Jersey City
DATE OF DEATH September 21, 1990