Howard Ward Dudley

Howard Ward Dudley (born October 30, 1887 in Derby , Derbyshire , † October 3, 1935 in London ) was a British biochemist .

Life

Dudley was the son of a clergyman, studied chemistry at the University of Leeds (with JB Cohen) and received his doctorate in 1912 at the University of Berlin in Emil Fischer's laboratory with Wilhelm Traube on the chemistry of purines . He then went to the laboratory of Christian A. Herter and Henry Dakin in New York, where he discovered the enzyme glyoxalase with Dakin . In 1914 he became a lecturer at the Animal Nutrition Research Institute in England and, after military service in World War I, at the Department of Biochemistry and Pharmacology at the National Institute of Medical Research in Hampstead (London) .

He found oxytocin and vasopressin among the hormones of the posterior lobe of the pituitary gland .

In 1922 he traveled with Henry Hallett Dale to Frederick Banting and Charles Best in Toronto and the Eli Lilly company in Indianapolis to learn about insulin production from the pancreas. Dudley developed an improved process that was used in the UK for industrial insulin production.

He isolated spermine from the human body, did research on histamine and found acetylcholine in the spleen.

He was a Fellow of the Royal Society .

literature

• Dudley, Howard Ward, in: Winfried R. Pötsch (lead), Annelore Fischer, Wolfgang Müller: Lexicon of important chemists , Harri Deutsch 1989, ISBN 978-3-817-11055-1 , p. 127.
• Obituary Notices Fellows Royal Society 1935, first page, JSTOR