Joachim Seelig

from Wikipedia, the free encyclopedia
Joachim Seelig, 2012

Joachim Heinrich Seelig (born March 29, 1942 in Cologne ) is a German physical chemist and specialist in NMR spectroscopy . He is one of the founding members of the Biozentrum of the University of Basel .

Life

Joachim Seelig studied chemistry and physics at the University of Cologne from 1961 to 1968 . In 1968 he did his doctorate with Manfred Eigen , Nobel Prize Winner for Chemistry, at the Max Planck Institute for Physical Chemistry in Göttingen. Afterwards, Seelig did research on electron spin resonance as a postdoctoral fellow at Stanford University in 1968/69 . In 1970 he moved to the Institute for Physical Chemistry at the University of Basel as a postdoctoral fellow , where he became group leader and assistant professor in 1972. In 1974 he became associate professor and from 1982 until his retirement in 2012 professor of structural biology at the Biozentrum of the University of Basel.

Act

Joachim Seelig developed biophysical methods to study the structure and thermodynamic properties of biological cell membranes . The interaction of proteins and lipids was EPR spectroscopy , deuterium - and phosphorus - nuclear magnetic resonance , neutron scattering and calorimetric investigated methods. The quantitative characterization of the biological membrane has become the international standard for further theoretical studies. His second area of ​​work was magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) in humans and animals. With C-13 NMR, the metabolism in the human and animal brain could be followed non-invasively . The tonotopy of the human brain has been described using rapid MRI imaging techniques .

Awards

  • 1987 Cloëtta Prize
  • 1991 Bijvoet Medal, Utrecht University, NL
  • 1994 Heinrich Wieland Prize , Munich
  • 2000 Applied Physical Chemistry Award 2000, European Society for Applied Physical Chemistry
  • 2005 Avanti Award in Lipids, Biophysical Society (USA)

Publications (selection)

  • A. Seelig and J. Seelig, The dynamic structure of fatty acyl chains in a phospholipid bilayer measured by deuterium magnetic resonance. In Biochemistry 13: 4839-4845 (1974), PMID 4371820 .
  • J. Seelig, PM Macdonald, and PG Scherer, Phospholipid head groups as sensors of electric charge in membranes. In Biochemistry 26, 7535-7541 (1987), PMID 3322401
  • N. Beckmann, I. Turkalij, J. Seelig and U. Keller, 13C NMR for the assessment of human brain glucose metabolism in vivo. In Biochemistry 30, 6362-6366 (1991), PMID 2054342
  • A. Ziegler, P. Nervi, M. Dürrenberger, and J. Seelig, The Cationic Cell-Penetrating Peptide CPP (TAT) Derived from the HIV-1 Protein TAT is Rapidly Transported into Living Fibroblasts: Optical, Biophysical, and Metabolic Evidence. In Biochemistry 44, 138-148 (2005), PMID 15628854
  • F. Zehender, A. Ziegler, H.-J. Schönfeld, and J. Seelig, Thermodynamics of protein self-association and unfolding, The case of apolipoprotein AI. In Biochemistry 51, 1269-1280 (2012), PMID 22320308

Web links

Individual evidence

  1. ↑ The origin and function of the Biozentrum. (PDF; 1.1 MB) at unigeschichte.unibas.ch, accessed on November 19, 2013
  2. ^ Emeriti of the Biozentrum
  3. ↑ Cloëtta Prize Winner ( Memento of the original from September 24, 2013 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. at cloetta-stiftung.ch, accessed on November 5, 2013  @1@ 2Template: Webachiv / IABot / www.cloetta-stiftung.ch
  4. ^ Heinrich Wieland Laureates heinrich-wieland-preis.de, accessed on January 10, 2016
  5. ^ Award “Applied Physical Chemistry” 2000 at eurostar-science.org, accessed on November 5, 2013
  6. ↑ Avanti Award in Lipids Winner ( Memento of the original from October 31, 2013 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. at biophysics.org, accessed November 5, 2013 @1@ 2Template: Webachiv / IABot / www.biophysics.org
personal data
SURNAME Seelig, Joachim
ALTERNATIVE NAMES Seelig, Joachim Heinrich (full name)
BRIEF DESCRIPTION German physical chemist and specialist in NMR spectroscopy
DATE OF BIRTH March 29, 1942
PLACE OF BIRTH Cologne