Julius Denzel

from Wikipedia, the free encyclopedia

Julius Denzel (born December 9, 1852 in Steinbach (now Wernau ) near Plochingen , † November 26, 1915 in Tübingen ) was a German chemist . He founded a chemical factory for ergot preparations in Tübingen with an attached analytical laboratory for food analysis.

Live and act

After attending secondary school in Esslingen , Julius Denzel initially became a pharmacist. He later studied in Strasbourg and Tübingen under Lothar Meyer , Wilhelm Rudolph Fittig , Rose and Friedrich August von Quenstedt . In 1876 he was licensed as a pharmacist, in 1878 he received his doctorate in natural sciences with a thesis on the chlorobromine substitution products of ethane and ethylene .

From 1880 to 1884 he worked as a pharmacist in London and as an assistant at the food inspection agency in Ulm . In 1884 he published a treatise on ergot and its active ingredients. In 1885 he started his own business in Tübingen. He founded his chemical factory there , to which he attached an analytical laboratory for food analysis. In 1894 he was certified as a food chemist. He procured a steam engine for the factory from the Ulrich Kohllöffel machine factory in Reutlingen .

With the help of the pharmacist John, the factory first made the ergot "Denzel" . The effectiveness of this preparation was tested by Saexingor, the former director of the Royal University Women's Clinic in Tübingen, and the Privy Senior Medical Councilor H. Fritsch, the former director of the Bonn University Women's Clinic . In pharmacological trade, ergotine "Denzel" is administered in three different forms: 50% ergotine in sterile solution, ergotine in vials and ergotine lozenges.

In order to make the healing effects of ergot, which is the basis of ergot, widely accessible at the high prices of this preparation, Julius Denzel, with the support of H. Fritsch, developed a preparation that essentially exploited the effectiveness of ergot, but was cheaper than ergotine and launched it in 1890 under the name Tinctura haemostyptica "Denzel" on the drug market . In addition to the initiator, H. Fritsch, Doederlein, formerly head of the University Women's Clinic in Tübingen, then in Munich, Sellheim in Tübingen, Kisch in Marienbad and Hofrat Benkiser in Karlsruhe repeatedly pointed out the importance of this tincture in specialist journals.

In 1898 Denzel had these two preparations followed by the preparation Digitalis "Denzel" (physiologically tested) , which received its first test by the assistant doctor of the medical university clinic in Tübingen, C. Mangold, under the then board member of Liebermeister, who received the results of these The examination results were made available to the general public in a lengthy scientific treatise.These examination results have been confirmed over the years by various medical professionals, including Otfried Müller, head of the Medical Clinic in Tübingen.

The following years were as busy and successful as the first years of the company, in which, among other things, the preparations Extr. Filicis ,, Denzel " , Kreosolid and Kreosolidpastillen with and without iron , as well as Frangol , were brought out, which in turn was inspired by a suggestion H. Fritsch owed him and through him also learned the scientific testing on patients.

He was introverted and therefore not predisposed to take an active part in public life. The serious and quiet work, in addition to the concern for the well-being of his family, completely filled the life of the active, reserved professional colleague.

Individual evidence

  1. ^ Journal of Applied Chemistry , Volume III, pp. 57-64, January 25, 1916; doi : 10.1002 / anie.19160290706 .
  2. Julius Denzel on TÜpedia. .
  3. ^ W. Staedel: About halogen substitution products of ethane and ethylene; Reports of the German Chemical Society, Volume 11, Issue 2, pp. 1735–1741, July – December 1878; doi : 10.1002 / cber.187801102134 .
  4. ^ Archives of Pharmacy 22, 2nd issue 1884.
  5. ^ Steam engines in the government district of Tübingen. .
  6. Therapeutic monthly notebooks , January 1891.