Leonard Lerman
Leonard Solomon Lerman (born June 27, 1925 in Pittsburgh , † September 19, 2012 ) was an American molecular biologist and geneticist who focused on the study of DNA .
Life
Leonard Lerman was born in Pittsburgh to Ukrainian-Jewish parents. Lerman was already scientifically active during his school days. In a science competition he won a scholarship to the Carnegie Institute of Technology (today: Carnegie Mellon University ), where he did his Bachelor of Science .
After World War II, he continued his studies at the California Institute of Technology and received a PhD in chemistry. He then moved to the University of Colorado School of Medicine to further research DNA. In 1959 Leonard Lerman took the opportunity to do a sabbatical at the Medical Research Council Laboratory of Molecular Biology in Cambridge ( UK ), where he worked with Sydney Brenner and Francis Crick , among others . In addition, Lerman conducted research at Vanderbilt University , the State University of New York in Albany and the Genetics Institute in Boston . He also served as a senior lecturer and PhD supervisor to Sidney Altman and Tom Maniatis at the Massachusetts Institute of Technology (MIT).
Lerman was also a member of the Genetics Institute, Inc. , the National Academy of Sciences and, since 1991, the American Academy of Arts and Sciences .
research
Leonard Lerman researched mainly in the field of molecular genetics and studied human DNA and its structure , among other things , he was also the first to define DNA mutation .
Fonts (selection)
- Lerman LS, Tolmach LJ: Genetic transformation. II. The significance of damage to the DNA molecule. In: Biochimica et Biophysica Acta. Volume 33 (2), 1959 pp. 371-87.
- Lerman LS: Structural considerations in the interactions of deoxyribonucleic acid and acridines. In: Journal of Molecular Biology. Volume 3, 1961, pp. 18-30.
- Lerman LS: The structure of the DNA-acridine complex. In: Proceedings of the National Academy of Sciences. Volume 49, 1963, pp. 94-102.
- Fischer SG and Lerman LS: Separation of random fragments of DNA according to properties of their sequences. In: Proceedings of the National Academy of Sciences. Volume 77, 1980, pp. 4420-4424.
- Fischer SG and Lerman LS: DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: Correspondence with melting theory. In: Proceedings of the National Academy of Sciences. Volume 80, 1983, pp. 1579-1583.
literature
- Leonard Lerman, a Pioneer in DNA Study, Is Dead at 87. The New York Times, September 29, 2012
- Leonard Lerman, former senior lecturer at MIT, dies at 87th MIT News, Sept. 28, 2012
- Leonard Lerman at cogap.de
- Leonard S. Lerman on dignitymemorialjewish.com
Individual evidence
| personal data | |
|---|---|
| SURNAME | Lerman, Leonard |
| ALTERNATIVE NAMES | Lerman, Leonard Solomon |
| BRIEF DESCRIPTION | American DNA researcher |
| DATE OF BIRTH | June 27, 1925 |
| PLACE OF BIRTH | Pittsburgh |
| DATE OF DEATH | 19th September 2012 |