Medifoxamine
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Non-proprietary name | Medifoxamine | ||||||||||||||||||
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Molecular formula | C 16 H 19 NO 2 | ||||||||||||||||||
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Molar mass | 257.33 g · mol -1 | ||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Medifoxamine is a drug that was used to treat depression before it was withdrawn from the market . It acts as a dopamine reuptake inhibitor and as an agonist at the 5HT 2A and 5HT 2C receptors . The Merck - daughter Lipha sales medifoxamine as part of a drug under the trade name Cledial .
Medifoxamine was mainly used in France . It was withdrawn from the market in 1999 because of rare but severe cases of liver damage .
Web links
Individual evidence
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ↑ Entry on medifoxamine in the ChemIDplus database of the United States National Library of Medicine (NLM), accessed on November 28, 2018.
- ^ S. Saleh, P. Turner: Ocular hypotensive effects of medifoxamine. In: Br J Clin Pharmacol . 34, 1992, pp. 269-271. PMID 1389953 .
- ↑ P. Martin, F. Lemonnier: Intérêt des récepteurs sérotoninergiques de type 2, 5-HT2A and 5-HT2C, dans les troubles dépressifs: action de la médifoxamine. In: Encephale. 20, 1994, pp. 427-435. PMID 7988407 .
- ^ PB Mitchell: Novel French antidepressants not available in the United States. In: Psychopharmacol Bull . 31, 1995, pp. 509-519. PMID 8668756 .
- ↑ Anonymous. Atteintes hépatiques sous médifoxamine. In: Prescrire. 19, 1999, pp. 591-592.
- ↑ G. Dumortier, W. Cabaret, L. Stamatiadis and others: Tolérance hépatique des antipsychotiques atypiques. In: Encephale. 28, 2002, pp. 542-551. PMID 12506267 .