Naftifin

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Structural formula
Naftifine.svg
General
Non-proprietary name Naftifin
other names

( E ) - N -Methyl- N - (naphthalen-1-ylmethyl) -3-phenylprop-2-en-1-amine ( IUPAC )

Molecular formula C 21 H 21 N
Brief description
  • Free base: Colorless, viscous oil
  • Hydrochloride: solid
External identifiers / databases
CAS number
PubChem 47641
DrugBank DB00735
Wikidata Q413586
Drug information
ATC code

D01 AE22

Drug class

Antifungal agent

properties
Molar mass 287.40 g · mol -1
Physical state

firmly

Melting point

177 ° C ( hydrochloride )

safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Naftifine is an antifungal that is used as a medicinal substance. Chemically, it is an allylamine - derivative .

application areas

Naftifine is a broad-spectrum antifungal agent that is used topically to treat tinea , a skin condition caused by thread fungi .

effect

It inhibits the ergosterol - synthesis by the enzyme squalene epoxidase blocked.

Trade names

Monopreparations

Exoderil (A)

Individual evidence

  1. a b c The Merck Index . An Encyclopaedia of Chemicals, Drugs and Biologicals. 14th edition, 2006, p. 1100, ISBN 978-0-911910-00-1 .
  2. This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.