Ergosterol

Structural formula
General
Non-proprietary name	Ergosterol
other names	(22 E ) -Ergosta-5,7,22-triene-3 β -ol; ERGOSTEROL ( INCI ) ;
Molecular formula	C 28 H 44 O
Brief description	white crystalline powder
External identifiers / databases
EC number	200-352-7
ECHA InfoCard	100,000,320
PubChem	444679
ChemSpider	392539
DrugBank	DB04038
Wikidata	Q143263
properties
Molar mass	396.65 g · mol -1
Physical state	firmly
Melting point	156-158 ° C
boiling point	250 ° C (1.3 Pa )
solubility	practically insoluble in water
safety instructions
GHS labeling of hazardous substances	no GHS pictograms
	no GHS pictograms
H and P phrases	H: 413
	P: no P-phrases
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Ergosterol , also called ergosterol , is a biochemically important natural substance from the group of sterols (sterols), more precisely the fungal mycosterols . It occurs in the cell membrane of fungi and mycoplasma .

biosynthesis

Biosynthesis of ergosterol (8) from lanosterol (1)

Ergosterol is a precursor ( provitamin ) of vitamin D ₂ (ergocalciferol), into which it can be converted photochemically by UV radiation ( e.g. sunlight ). This connection was discovered in 1927 by the Göttingen chemist Adolf Windaus ( Nobel Prize for Chemistry 1928) and was thoroughly investigated in the following years; the structural formula could be clarified in 1934.

A study published in 2009 study suggests that the ergosterol content in house dust as a rapid method for the detection of a mold infestation in interiors can be used.

Individual evidence

↑ Entry on ERGOSTEROL in the CosIng database of the EU Commission, accessed on April 2, 2020.
↑ ^a ^b ^c data sheet ergosterol from Acros, accessed on February 21, 2010.
↑ Ergosterin data sheet at AlfaAesar, accessed on February 21, 2010 ( PDF )(JavaScript required) .

↑ ^a ^b Ergosterol data sheet from Sigma-Aldrich , accessed on August 14, 2014 ( PDF ).

↑ Ilka Toepfer, Werner Butte: Chemical indicators for mold in house dust . Hazardous substances - keeping air clean 69 (3), pp. 91–95 (2009), ISSN 0949-8036 .

[CosIng-1] Entry on ERGOSTEROL in the CosIng database of the EU Commission, accessed on April 2, 2020.

[acros-2] ta sheet ergosterol from Acros, accessed on February 21, 2010.

[alfa-3] Ergosterin data sheet at AlfaAesar, accessed on February 21, 2010 ( PDF )(JavaScript required) .

[Sigma-4] Ergosterol data sheet from Sigma-Aldrich , accessed on August 14, 2014 ( PDF ).

[5] Ilka Toepfer, Werner Butte: Chemical indicators for mold in house dust . Hazardous substances - keeping air clean 69 (3), pp. 91–95 (2009), ISSN 0949-8036 .