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Niessen or Nießen is the family name of the following people:
- Alfred Ernst von Niessen (1901–1978), German engineer and shovel manufacturer
- Bruno von Niessen (1902–1981), German musician, director and opera director
- Carl Niessen (1890–1969), German theater scholar
- Charly Niessen (1923–1990), Austrian pop composer and songwriter
- Claudia Niessen (* 1979), Belgian politician
- Claudius Nießen (* 1980), German author, editor and cultural manager
- Gabriele Nießen (* 1964), German urban planner and Bremen State Councilor
- Hans Niessen (* 1950), Belgian politician
- Hans-Lutz Niessen (1920–1982), Dutch guitarist, composer and music teacher
- Helga Niessen , birth name of Helga Masthoff (* 1941), German tennis player
- Helga Maria Niessen (* 1954), German author and politician
- Hildegard Nießen (* 1946), German politician (SPD)
- Johannes Niessen (1821–1910), German history painter
- Jörg Nießen (* 1975), German firefighter, paramedic and bestselling author
- Josef Niessen (1922–1994), German arranger and composer
- Karel Niessen (1895–1967), Dutch physicist
- Leonore Niessen-Deiters (1879–1939), German journalist and writer
- Paul von Nießen (1857–1937), German high school teacher and historian
- Wolfgang von Niessen (* 1941), German theoretical chemist and university professor
See also:
