1-bromoperfluorooctane

Structural formula
General
Surname	1-bromoperfluorooctane
other names	1-bromoheptadecafluorooctane; Perfluorooctyl bromide; Perflubron; PFOB; PERFLUOROCAPRYLYL BROMIDE ( INCI ) ;
Molecular formula	C 8 F 17 Br
Brief description	light yellow liquid
External identifiers / databases
EC number	207-028-4
ECHA InfoCard	100.006.391
PubChem	9873
ChemSpider	9489
DrugBank	DB05791
Wikidata	Q2190150
Drug information
ATC code	V08 CX01
properties
Molar mass	498.98 g mol −1
Physical state	liquid
density	1.930 g cm −3
Melting point	6 ° C
boiling point	141-143 ° C
solubility	practically insoluble in water
Refractive index	1.3050 (20 ° C)
safety instructions
	Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances Caution
H and P phrases	H: 315-319-335
	P: 261-280-305 + 351 + 338-304 + 340-405-501
Toxicological data	14,720 mg kg −1 ( LD 50 , mouse , iv )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

1-bromoperfluorooctane is a chemical compound from the group of perfluorocarbons .

Extraction and presentation

1-Bromperfluoroctan, by telomerization of tetrafluoroethylene about one-Iodperfluoroctan be won.

properties

1-bromoperfluorooctane is a liquid that is practically insoluble in water.

use

1-bromoperfluorooctane can be used as a contrast agent in medicine. The compound is also being investigated as an oxygen carrier and can be used for chemical syntheses.

Individual evidence

↑ Entry on PERFLUOROCAPRYLYL BROMIDE in the CosIng database of the EU Commission, accessed on May 22, 2020.
↑ ^a ^b Data sheet 1-Bromoheptadecafluorooctane, 99% from Sigma-Aldrich , accessed on June 25, 2017 ( PDF ).
↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Data sheet 1-Bromoperfluorooctane, 98 +% from AlfaAesar, accessed on June 25, 2017 ( PDF )(JavaScript required) .
↑ Erik Kissa: Fluorinated Surfactants and Repellents, Second Edition . CRC Press, 2001, ISBN 978-0-8247-0472-8 , pp. 474 ( limited preview in Google Book search).
↑ Donat R Spahn: Blood substitutes Artificial oxygen carriers: perfluorocarbon emulsions In: Critical Care. 3, p. R93, doi : 10.1186 / cc364 .
↑ John A. Gladysz, Dennis P. Curran, Istv? N T. Horv? Th: Handbook of Fluorous Chemistry . John Wiley & Sons, 2006, ISBN 978-3-527-60449-4 , pp. 58 ( limited preview in Google Book search).

[CosIng-1] Entry on PERFLUOROCAPRYLYL BROMIDE in the CosIng database of the EU Commission, accessed on May 22, 2020.

[Sigma-2] Data sheet 1-Bromoheptadecafluorooctane, 99% from Sigma-Aldrich , accessed on June 25, 2017 ( PDF ).

[Alfa-3] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Data sheet 1-Bromoperfluorooctane, 98 +% from AlfaAesar, accessed on June 25, 2017 ( PDF )(JavaScript required) .

[Erik_Kissa-4] Erik Kissa: Fluorinated Surfactants and Repellents, Second Edition . CRC Press, 2001, ISBN 978-0-8247-0472-8 , pp. 474 ( limited preview in Google Book search).

[DOI10.1186/cc364-5] Donat R Spahn: Blood substitutes Artificial oxygen carriers: perfluorocarbon emulsions In: Critical Care. 3, p. R93, doi : 10.1186 / cc364 .

[John_A._Gladysz,_Dennis_P._Curran,_Istv?n_T._Horv?th-6] John A. Gladysz, Dennis P. Curran, Istv? N T. Horv? Th: Handbook of Fluorous Chemistry . John Wiley & Sons, 2006, ISBN 978-3-527-60449-4 , pp. 58 ( limited preview in Google Book search).