Phenazepam

Structural formula
General
Surname	Phenazepam
other names	7-bromo-5- (2-chlorophenyl) -1,3-dihydro-1,4-benzodiazepin-2-one ( IUPAC ); Fenazepam;
Molecular formula	C 15 H 10 BrClN 2 O
External identifiers / databases
EC number	682-231-2
ECHA InfoCard	100.207.405
PubChem	40113
ChemSpider	36657
Wikidata	Q421138
Drug information
Drug class	Benzodiazepine; Anxiolytic; Anti-epileptic;
properties
Molar mass	349.61 g · mol -1
safety instructions
H and P phrases	H: 319-340-360-362
	P: ?
Toxicological data	2400 mg kg −1 ( LD 50 , mouse , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Phenazepam is a drug from the group of benzodiazepines .

Phenazepam was developed in the Soviet Union and is still produced today in Russia and neighboring countries. Phenazepam is used for neurological disorders such as epilepsy , but also as an antidote for alcohol withdrawal symptoms and insomnia. It is also used as a premedication in surgical interventions, as it increases the effect of the anesthetic and, like most benzodiazepines, has an anxiolytic (anxiolytic) effect. In Germany, phenazepam is not used in pharmacy, but has appeared as a designer drug.

Side effects

Common side effects are nausea, ataxia, and drowsiness. Similar to other benzodiazepines, sudden discontinuation after long-term therapy is associated with severe withdrawal symptoms.

Legal status

Phenazepam does not appear in legislation in either the USA or Great Britain, although benzodiazepines are subject to strict controls in these countries. According to official information, the pilot of Crossair Flight 498 under the influence of phenazepam could have caused the plane to crash.

Germany

With the 27th Narcotics Amendment Ordinance, Phenazepam was made subject to the Narcotics Act in Germany as a prescription narcotic .

Individual evidence

↑ Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A label of [No public or meaningful name is available] in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on April 18, 2018, is derived from a self-classification by the distributor .
^ Entry on phenazepam in the ChemIDplus database of the United States National Library of Medicine (NLM), accessed on April 18, 2018.
^ Federal Department for the Environment, Transport, Energy and Communication: Final report by the Aircraft Accident Investigation Bureau. ( Memento of the original from February 16, 2012 on WebCite ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. (PDF; 968 kB) No. 1781, p. 95. @1@ 2

^ Federal Ministry of Health: Cabinet adopts 27th Narcotics Amendment Ordinance . Press release of May 22, 2013, accessed on May 26, 2013.

[1] Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A label of [No public or meaningful name is available] in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on April 18, 2018, is derived from a self-classification by the distributor .

[ChemIDplus-2] Entry on phenazepam in the ChemIDplus database of the United States National Library of Medicine (NLM), accessed on April 18, 2018.

[3] Federal Department for the Environment, Transport, Energy and Communication: Final report by the Aircraft Accident Investigation Bureau. ( Memento of the original from February 16, 2012 on WebCite ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. (PDF; 968 kB) No. 1781, p. 95. @1@ 2

[4] Federal Ministry of Health: Cabinet adopts 27th Narcotics Amendment Ordinance . Press release of May 22, 2013, accessed on May 26, 2013.