Phosphoethanolamine

Structural formula
General
Surname	Phosphoethanolamine
other names	2-aminoethyl dihydrogen phosphate O -phosphocolamine O -phosphoethanolamine O -phosphorylethanolamine Colamine phosphoric acid Phosphorylcolamine
Molecular formula	C 2 H 8 NO 4 P
Brief description	light yellow powder
External identifiers / databases
CAS number 1071-23-4 EC number 213-988-5 ECHA InfoCard 100.012.717 PubChem 1015 DrugBank DB01738 Wikidata Q418826
properties
Molar mass	141.06 g mol −1
Physical state	firmly
Melting point	241-243 ° C
safety instructions
GHS labeling of hazardous substances danger H and P phrases H: 301-314 P: 280-301 + 310-305 + 351 + 338-310
Toxicological data	639 mg kg −1 ( LD 50 ,  mouse ,  iv )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Phosphoethanolamine is the phosphoric acid ester of monoethanolamine . It occurs as a structural section, for example in phosphatidylethanolamines and is a breakdown product of sphingosine-1-phosphate .

presentation

Phosphoethanolamine can be produced by the reaction of oxazolidin-2-one with phosphoric acid.

Another synthetic route is the ring opening of aziridine by phosphoric acid.

Individual evidence

1. ↑ ^{a b c d e} data sheet O-Phosphorylethanolamine from Sigma-Aldrich , accessed on October 16, 2016 ( PDF ).
2. ^ Jones, in: Chemistry and Industry 1956 , 1454.
3. ↑ HN Christensen: Synthesis of esters of phosphoric acid related zp phosphadites , in: J. Biol. Chem. 1940 , 135 , 399-401.