Pyrithyldione

Structural formula
General
Non-proprietary name	Pyrithyldione
other names	3,3-diethyl-1 H -pyridine-2,4-dione
Molecular formula	C 9 H 13 NO 2
External identifiers / databases
CAS number 77-04-3 EC number 201-000-5 ECHA InfoCard 100,000,910 PubChem 4994 Wikidata Q408959
Drug information
ATC code	N05 CE03
Drug class	Hypnotic , sedative
properties
Molar mass	167.21 g mol −1
Physical state	firmly
Melting point	187-189 ° C (18.7 Pa )
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed GHS labeling of hazardous substances Caution H and P phrases H: 302-312-332 P: 261-280-322-301 + 312-304 + 340-501
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Pyrithyldione is a medicinal substance that has a calming and sleep-inducing effect. Medicines containing pyrithyldione are no longer on the market worldwide. The active ingredient was marketed by Roche under the name Persedon , but it caused agranulocytosis more frequently .

Historical Persedon packaging

Like glutethimide , methyprylon and thalidomide (trade name Contergan ^® ), pyrithyldione belongs to the piperidinediones , which differ from the barbiturates by replacing a lactam group (–CO – NH–) with –CH ₂ –CH ₂ - or –CH = CH– distinguish.

Pyrithyldione hit the headlines in 1987 in connection with the death of Uwe Barschel when it was found in his corpse along with other substances.

Individual evidence

1. ↑ Pyrithyldione data sheet at Acros, accessed on January 27, 2008.
2. ↑ ^{a b} lgcstandards: Pyrithyldione ( Memento from October 31, 2016 in the Internet Archive )
3. ↑ Eberhard Schröder, Clemens Rufer, Ralph Schmiechen, Arzneimittelchemie I, Georg Thieme Verlag 1976 ISBN 3-13-520601-7

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !