Methyprylon
Structural formula | |||||||||||||||||||
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1: 1 mixture of ( R ) -methyprylon (left) and ( S ) -methyprylon (right) | |||||||||||||||||||
General | |||||||||||||||||||
Non-proprietary name | Methyprylon | ||||||||||||||||||
other names |
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Molecular formula | C 10 H 17 NO 2 | ||||||||||||||||||
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Drug information | |||||||||||||||||||
ATC code | |||||||||||||||||||
Drug class |
Sedative, hypnotic |
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properties | |||||||||||||||||||
Molar mass | 183.26 g mol −1 | ||||||||||||||||||
Physical state |
firmly |
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Melting point |
84.5 ° C ( polymorphic ) |
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solubility |
soluble in water, ethanol , diethyl ether and chloroform |
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safety instructions | |||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Methyprylon is a drug that has been used as a sedative and hypnotic . It was patented by Hoffmann-La Roche in 1954 and had been on the market in Germany under the trade name Noludar ® since 1955.
From a chemical point of view, it belongs to the group of piperidinediones , just like glutethimide , pyrithyldione and thalidomide . These, in turn, are structural modifications of the barbiturates .
Mechanism of action
The duration of action of Methyprylon corresponds to that of medium-effective barbiturates. It has no advantages over these.
unwanted effects
Long-term use can lead to dependence .
Legal status
Methyprylon is listed in Appendix II of the German Narcotics Act and is therefore one of the marketable but not prescription narcotics.
literature
- Entry to Methyprylon. In: Römpp Online . Georg Thieme Verlag, accessed on January 2, 2015.
- HJ Roth, H. Fenner: Medicines . Thieme, Stuttgart a. New York, 1988. pp. 270-271.
Individual evidence
- ↑ a b H. PT Ammon (Hrsg.): Hunnius Pharmaceutical Dictionary . 9th edition, Walter de Gruyter, Berlin a. New York, 2004. pp. 987. ISBN 978-3-11-017475-5 .
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ↑ Psychiatric Drugs Timeline