R. John Ellis

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Reginald John Ellis (born February 12, 1935 ) is a British biologist and professor emeritus at the University of Warwick , Coventry .

Life

Ellis received a Ph.D. from David Denison Davies at King's College London in 1960. with a thesis on transamination . As a postdoctoral fellow he worked on sulfate reduction with Charles A. Pasternak at Oxford University . In 1964, Ellis went to the Department of Botany and Biochemistry at the University of Aberdeen , before moving to the newly established Department of Life Sciences (Biological Sciences) at the University of Warwick in Coventry in 1970 as head of the group on chloroplasts . Here he received a professorship in 1976. In 1996 he retired.

Act

Ellis was considered a leading researcher in the field of the biogenesis of chloroplasts , the biochemistry of which he researched in higher plants. In 1980 he discovered the first molecular chaperone that helped assemble subunits of the Rubisco . Franz-Ulrich Hartl and Arthur Horwich were able to build on Ellis' work . Ellis was able to significantly expand his knowledge of the chaperones, which are necessary in a wide range of cellular processes.

Ellis' work is fundamental to understanding diseases caused by disorders of protein folding , including Alzheimer's disease and cystic fibrosis .

His work Molecular chaperones from 1991 is one of the most cited works in molecular biology .

Awards

Fonts (selection)

Web links

Individual evidence

  1. Molecular chaperones: how cells stop proteins from misbehaving at royalsociety.org; Retrieved February 15, 2011
  2. ^ Ellis, Reginald John at the International Center for Scientific Research ; Retrieved February 15, 2011
  3. ^ Ellis RJ, van der Vies SM: Molecular chaperones . In: Annu. Rev. Biochem. . 60, 1991, pp. 321-47. doi : 10.1146 / annurev.bi.60.070191.001541 . PMID 1679318 .
  4. ^ Molecular Self-Assembly. Letter Commentary by Emeritus Professor R. John Ellis, FRS ( Memento October 4, 2008 in the Internet Archive ) at esi-topics.com; Retrieved February 15, 2011
  5. ^ Fellows of the Royal Society at royalsociety.org; Retrieved February 15, 2011
  6. ^ R. John Ellis, PhD at the Gairdner Foundation (gairdner.org); Retrieved December 15, 2012