R. John Ellis
Reginald John Ellis (born February 12, 1935 ) is a British biologist and professor emeritus at the University of Warwick , Coventry .
Life
Ellis received a Ph.D. from David Denison Davies at King's College London in 1960. with a thesis on transamination . As a postdoctoral fellow he worked on sulfate reduction with Charles A. Pasternak at Oxford University . In 1964, Ellis went to the Department of Botany and Biochemistry at the University of Aberdeen , before moving to the newly established Department of Life Sciences (Biological Sciences) at the University of Warwick in Coventry in 1970 as head of the group on chloroplasts . Here he received a professorship in 1976. In 1996 he retired.
Act
Ellis was considered a leading researcher in the field of the biogenesis of chloroplasts , the biochemistry of which he researched in higher plants. In 1980 he discovered the first molecular chaperone that helped assemble subunits of the Rubisco . Franz-Ulrich Hartl and Arthur Horwich were able to build on Ellis' work . Ellis was able to significantly expand his knowledge of the chaperones, which are necessary in a wide range of cellular processes.
Ellis' work is fundamental to understanding diseases caused by disorders of protein folding , including Alzheimer's disease and cystic fibrosis .
His work Molecular chaperones from 1991 is one of the most cited works in molecular biology .
Awards
- 1983 membership in the Royal Society
- 2004 Gairdner Foundation International Award
- 2011 Croonian Lecture
Fonts (selection)
- The Chaperonins. Academic Press Inc. 1996, ISBN 978-0-12-237455-5
- How Science Works: Evolution. Springer Netherlands 2010, ISBN 978-90-481-3182-2
Web links
- Professor R John Ellis FRS at the University of Warwick (warwick.ac.uk); Retrieved February 15, 2011
Individual evidence
- ↑ Molecular chaperones: how cells stop proteins from misbehaving at royalsociety.org; Retrieved February 15, 2011
- ^ Ellis, Reginald John at the International Center for Scientific Research ; Retrieved February 15, 2011
- ^ Ellis RJ, van der Vies SM: Molecular chaperones . In: Annu. Rev. Biochem. . 60, 1991, pp. 321-47. doi : 10.1146 / annurev.bi.60.070191.001541 . PMID 1679318 .
- ^ Molecular Self-Assembly. Letter Commentary by Emeritus Professor R. John Ellis, FRS ( Memento October 4, 2008 in the Internet Archive ) at esi-topics.com; Retrieved February 15, 2011
- ^ Fellows of the Royal Society at royalsociety.org; Retrieved February 15, 2011
- ^ R. John Ellis, PhD at the Gairdner Foundation (gairdner.org); Retrieved December 15, 2012
personal data | |
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SURNAME | Ellis, R. John |
ALTERNATIVE NAMES | Ellis, John; Ellis, Reginald John |
BRIEF DESCRIPTION | British biologist |
DATE OF BIRTH | February 12, 1935 |