Richard H. Scheller

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Richard H. Scheller (born October 30, 1953 in Milwaukee ) is an American biochemist and neuroscientist.

Live and act

Scheller studied at the University of Wisconsin (Bachelor in Biochemistry 1975) and received his PhD in Chemistry from the California Institute of Technology (Caltech) in 1980 . As a post-doctoral student he was at Caltech in 1980/81 and at Columbia University in 1981/82 with the later Nobel Prize winners Eric Kandel and Richard Axel , where he turned to neuroscientific research. In 1982 he became an Assistant Professor, 1987 Associate Professor and 1994 Professor of Molecular and Cellular Physiology and Biology at Stanford University . There he also did research from 1994 for the Howard Hughes Medical Institute (HHMI) at Stanford University Medical Center. In 1984 he became a research fellow of the Alfred P. Sloan Foundation ( Sloan Research Fellow ). He has been with Genentech since 2001 , initially as Senior Vice President and from 2003 as Executive Vice President, responsible for research strategy, discovery of new drugs and their early (clinical) tests. In 2008 he became Chief Scientific Officer there. He is also on the Executive Committee of parent company Roche and the Research Review Committee of Genentech.

Since 2004, in addition to his management position at Genentech, he has also been Adjunct Professor in the Department of Biochemistry and Biophysics at the University of California, San Francisco .

Scheller turned to neuroscience as a post-doctoral student with Kandel and Axel at Columbia University - although he had hardly been trained in this before. He used genetic engineering methods to identify the genes responsible for signaling molecules in the nervous system ( neuropeptides ) and identified and cloned genes for proteins that control the release of neurotransmitters. At Genentech, he mainly researched proteins that control the transport of structures in cells (Rab GTPases).

He published over 200 scientific articles (2011).

In 2010 he received the Kavli Prize in Neuroscience with Thomas C. Südhof and James E. Rothman for showing how networks of nerve cells in the spinal cord of mammals generate elementary rhythmic motor movements. In 1997 he received the National Academy of Sciences Award in Molecular Biology and in 1993 he gave the W. Alden Spencer Lecture (with Thomas Südhof).

He is a member of the National Academy of Sciences (2000) and the American Academy of Arts and Sciences (1998) as well as the Norwegian Academy of Sciences . He is on the National Advisory Mental Health Council of the National Institutes of Health. In 2009 he received the Distinguished Alumni Award in Biology from the University of Wisconsin-Madison. In 2013 he received the Albert Lasker Award for Basic Medical Research .

Web links

Individual evidence

  1. Career data according to Pamela Kalte u. a. American Men and Women of Science , Thomson Gale 2005
  2. 2010 Kavli Prize Laureates in Neuroscience. In: kavliprize.org. Retrieved April 27, 2017 (English).