Robert H. Abeles
Robert Heinz Abeles (born January 14, 1926 in Vienna , Austria ; † June 18, 2000 ) was an American chemist who researched in particular the mode of action of enzymes .
Life
Abeles came to Chicago as a refugee with his family in the United States in 1939 . During the Second World War he was a soldier in Europe (where he worked as an interpreter for interrogations of German prisoners of war ). He studied chemistry at the University of Chicago , graduating with a master's degree in 1950. In 1955, he received his doctorate in biochemistry from the University of Colorado with Cosmo G. Mackenzie . As a post-doctoral student , he was with Frank Westheimer at Harvard University . In 1957 he was Assistant Professor at Ohio State University , 1960 Assistant Professor (later Associate Professor) at the University of Michigan and 1964 Associate Professor and later Professor of Biochemistry at Brandeis University . With William Jencks (1927–2007) he made Brandeis a center for enzyme research.
Abeles discovered the effect of whole classes of enzymes in biochemistry, including the effect of the vitamin B 12 coenzyme . In addition, he developed enzyme inhibitors, which also provided approaches for new drugs. For example, he developed the first suicide inactivators, which initially act like the original enzymes, but then lead to the inactivation of the enzyme.
In 1995 he received the Welch Award in Chemistry , 1987 the Edward E. Swissman-Bristol Myers Award in Medicinal Chemistry, 1988 the Repligen Award in the Chemistry of Biological Processes, 1990 the Alfred E. Bader Award of the American Chemical Society , and 1994 the William Rose Award and in 1994 the Alexander von Humboldt Senior Scientist Award. He was an honorary doctor of the University of Chicago and a member of the National Academy of Sciences , the American Philosophical Society, and the American Academy of Arts and Sciences .
After Robert Abeles suffered from Hodgkin's disease , Parkinson's disease came at the end of his life .
Web links
- Obituary at the American Philosophical Society, pdf ( Memento from September 14, 2012 in the Internet Archive )
Individual evidence
- ^ Biographical data, publications and academic family tree of Robert Heinz Abeles at academictree.org, accessed on January 1, 2018.
| personal data | |
|---|---|
| SURNAME | Abeles, Robert H. |
| ALTERNATIVE NAMES | Abeles, Robert Heinz |
| BRIEF DESCRIPTION | American chemist |
| DATE OF BIRTH | January 14, 1926 |
| PLACE OF BIRTH | Vienna |
| DATE OF DEATH | June 18, 2000 |