Salicyluric acid
Structural formula | |||||||||||||||||||
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General | |||||||||||||||||||
Surname | Salicyluric acid | ||||||||||||||||||
other names |
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Molecular formula | C 9 H 9 NO 4 | ||||||||||||||||||
Brief description |
white solid |
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properties | |||||||||||||||||||
Molar mass | 195.17 g mol −1 | ||||||||||||||||||
Physical state |
firmly |
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Melting point |
167-169 ° C |
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solubility |
poorly soluble in water (1.8 g / l at 20 ° C) |
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safety instructions | |||||||||||||||||||
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Toxicological data | |||||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Salicyluric acid (saliglycic acid), C 9 H 9 NO 4 , is an amide of salicylic acid with glycine . Chemically, it is also a derivative of hippuric acid . Salicyluric acid is formed in the liver after ingestion of salicylic acid preparations, whereby up to 70% of the salicylic acid is converted into salicyluric acid. It is excreted in the urine.
Salicyluric acid crystallizes out of the hot aqueous solution in concentrically grouped needles. Salicyluric acid has a bitter taste, is acidic, and dissolves in hot water, ethanol and diethyl ether . It can be detected in solution by means of iron (III) salts, e.g. B. ferric chloride . If the result is positive, purple complexes form. After long boiling, salicyluric acid breaks down into salicylic acid and glycine.
Individual evidence
- ↑ a b c d e data sheet o-Hydroxyhippuric acid, analytical standard from Sigma-Aldrich , accessed on December 26, 2019 ( PDF ).
- ↑ a b Entry on salicylic acid. In: Römpp Online . Georg Thieme Verlag, accessed on June 7, 2014.
- ↑ a b c L. Gmelin : Handbuch der Chemie, Volume 6 , pp. 257-258, University bookstore by Karl Winter, 1859 .
- ↑ B. Brinkmann (ed.), B. Madea (ed.): Handbook of judicial medicine Volume 2 , p. 322, 1st edition, Springer Verlag Berlin, 2003 , ISBN 978-3-540-66447-5 .