Simplex virus
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Herpes simplex virus in a TEM image |
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The genus Simplexvirus comprises virus species of the family Herpesviridae , which have a very uniform phylogeny within the subfamily Alphaherpesvirinae with regard to their genome sequence . Most simplex viruses infect primates and (with the exception of the herpes virus simiae ) are closely adapted to a host . In cell culture , however, they can infect a large number of cells from a wide variety of species in vitro . Here they always cause a cytopathic effect .
All simplex viruses persist in nerve cells of the host for life and can reactivate from there. They show a close relationship between the surface epitopes and therefore also a cross-reaction in serological tests.
The genus is named after its type species , the human herpes simplex virus (scientifically human alphaherpesvirus 1 ), which, among other things , causes herpes simplex (Latin simplex : simple, plain) as a disease.
Systematics
The system of the genus according to the definition of the ICTV as of November 2018 comprises twelve individual virus species:
- Subfamily Alphaherpesvirinae
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- Genus simplex virus
- Species Atelines herpesvirus 1 or spider herpesvirus 1 (ATHV-1) s. Ateline alphaherpesvirus 1
- Species Bovine Herpes Virus 2 or bovine herpesvirus 2 (BoHV-2), en. Bovine alphaherpesvirus 2
- Species Cercopithecines Herpesvirus 1 (CeHV-1 or CHV-1) or Herpesvirus simiae , Herpes B virus , Macacine alphaherpesvirus 1
- Species Cercopithecines Herpesvirus 2 (CeHV-2), en. Cercopithecine alphaherpesvirus 2
- Species Cercopithecines Herpesvirus 16 (CeHV-16) or Herpesvirus papio , en. Papiine alphaherpesvirus 2
- Species Human Herpes Virus 1 (HHV-1) or Herpes Simplex Virus 1 (HSV-1), en. Human alphaherpesvirus 1
- Species Human Herpes Virus 2 (HHV-2) or Herpes Simplex Virus 2 (HSV-2), en. Human alphaherpesvirus 2
- Species kangaroo herpesvirus 1 or Parma wallaby herpesvirus , macropodid herpesvirus 1 (MaHV-1), en. Macropodid alphaherpesvirus 1
- Species kangaroo herpesvirus 2 or Dorcopsis wallaby herpesvirus , macropodid herpesvirus 2 (MaHV-2), en. Macropodid alphaherpesvirus 2
- Species Leporid alphaherpesvirus 4 obsolete Leporid herpesvirus 4
- Species Panine alphaherpesvirus 3 obsolete Panine herpesvirus
- Species Saimiriines Herpesvirus 1 (SaHV-1) or Marmoset Herpesvirus , Herpesvirus tamarinus , en. Saimiriine alphaherpesvirus 1
swell
- CM Fauquet, MA Mayo, et al. : Eighth Report of the International Committee on Taxonomy of Viruses . London, San Diego, 2005 ISBN 0-12-249951-4 pp. 199f
Individual evidence
- ↑ a b c d e ICTV: ICTV Taxonomy history: Human alphaherpesvirus 1 , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)
- ↑ ICTV : Master Species List 2018a v1 MSL including all taxa updates since the 2017 release. Fall 2018 (MSL # 33)
Web links
- Genus simplex virus ( NCBI Taxonomy)
- Simplex virus in the ICTV database
- Simplex virus (Big Picture Book of Viruses)
- Simplex virus on ViralZone (Swiss Institute for Bioinfirmatics, SIB)