Treponema
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| Treponema | ||||||||||||
| ( Schaudinn 1905) Abt, Göker & Klenk 2013 |
Treponema is a genus of gram-negative bacteria from the phylum (the division) of the spiral spirochetes .
Like all spirochetes, Treponema also has peculiarly constructed, helically twisted mobile cells. The cell wall has a layer of glucosamine-glycan and high levels of cardiolipin .
Representatives that live parasitically or as commensals in warm-blooded animals have a narrow temperature range of 30 ° C to 37 ° C. In addition, they are sensitive to high oxygen concentrations, they are microaerophilic . The optimal pH is between 7.2 and 7.4.
Treponema primitia and related species are important inhabitants of the rectum of wood-eating termites . Here they form acetate through reductive processes and play a key role in the carbon turnover.
The Treponema species are the cause of tropical Treponematoses , for the therapy of which penicillins can be used. The best-known representative of Treponema is Treponema pallidum , the causative agent of syphilis . Pinta is caused by the subspecies Treponema (pallidum) carateum . Treponema pertenue is the name of the causative agent of yaws . Treponema paraluiscuniculi is the causative agent of rabbit syphilis . Treponema denticola and Treponema brennaborense play a decisive role in skin inflammation in cattle . Furthermore, Treponema denticola has great pathogenic potency in the area of the teeth holding apparatus ( periodontium ) of humans.
swell
- Bak, Matthew. "Treponema pallidum: The Etiologic Agent of Syphilis." February 7, 2006
- "Syphilis CDC Fact Sheet ." Centers for Disease Control and Prevention. May 2004. Centers for Disease Control and Prevention. February 7, 2006.
- Barbara I. Tshisuaka: Treponema. In: Werner E. Gerabek , Bernhard D. Haage, Gundolf Keil , Wolfgang Wegner (eds.): Enzyklopädie Medizingeschichte. De Gruyter, Berlin / New York 2005, ISBN 3-11-015714-4 , p. 1418 f.
Individual evidence
- ↑ Michael N. Sela, Role of Treponema Denticola in Periodontal Diseases, Critical Reviews in Oral Biology & Medicine, 2001, vol. 12, no.5, 399-413