1,10-dichlorodecane

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Structural formula
Structural formula of 1,10-dichlorodecane
General
Surname 1,10-dichlorodecane
other names

Decamethylene dichloride

Molecular formula C 10 H 20 Cl 2
Brief description

colorless liquid

External identifiers / databases
CAS number 2162-98-3
EC number 218-489-6
ECHA InfoCard 100.016.809
PubChem 75101
Wikidata Q57981763
properties
Molar mass 211.17 g mol −1
Physical state

liquid

density

0.999 g cm −3 (25 ° C)

Melting point

15.6 ° C

boiling point

167-168 ° C (28 mmHg)

Refractive index

1.4605 (20 ° C)

safety instructions
GHS labeling of hazardous substances
no GHS pictograms
H and P phrases H: 413
P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

1,10-dichlorodecane is a chemical compound from the group of aliphatic , saturated halogenated hydrocarbons .

Extraction and presentation

1,10-dichlorodecane can be obtained by decarboxylation of the corresponding alkychloroformate. The compound can also be prepared by reacting 1,10-decanediol with thionyl chloride .

properties

1,10-dichlorodecane is a colorless liquid. Some bacteria can break down the compound well.

use

1,10-dichlorodecane is used as an intermediate in the manufacture of drugs ( e.g. tiadenol ).

Individual evidence

  1. ↑ a b c d e f g h i data sheet 1,10-dichlorodecane, 99% from Sigma-Aldrich , accessed on October 29, 2018 ( PDF ).
  2. ↑ Science of Synthesis: Houben-Weyl Methods of Molecular Transformations Vol. 35 Chlorine, Bromine, and Iodine . Georg Thieme Verlag, 2014, ISBN 3-13-172121-9 , p. 64 ( limited preview in Google Book search).
  3. ^ Scientific Papers of the Institute of Physical and Chemical Research . The Institute, 1931, p. 12 ( limited preview in Google Book search).
  4. ↑ C. Wischnak, FE Löffler, J. Li, JW Urbance, R. Müller: Pseudomonas sp. strain 273, an aerobic alpha, omega-dichloroalkane Degrading bacterium. In: Appl. Environ. Microbiol. 64, 1998, pp. 3507-3511, PMID 9726906 </ PMC 106756 < (free full text).
  5. ^ A. Kleemann, J. Engel, B. Kutscher, D. Reichert: Pharmaceutical Substances, 5th Edition, 2009 Syntheses, Patents and Applications of the most relevant APIs . Georg Thieme Verlag, 2014, ISBN 3-13-179525-5 , pp. 1601 ( limited preview in Google Book Search).