1-acetyl-2-phenylhydrazine

Structural formula
General
Surname	1-acetyl-2-phenylhydrazine
other names	2'-phenylacetohydrazide; N -acetyl- N '-phenylhydrazine;
Molecular formula	C 8 H 10 N 2 O
Brief description	white solid
External identifiers / databases
EC number	204-055-3
ECHA InfoCard	100.003.687
PubChem	8247
Wikidata	Q2806574
properties
Molar mass	150.18 g mol −1
Physical state	firmly
density	1.14 g cm −3
Melting point	128-131 ° C
solubility	soluble in ethanol
Refractive index	1.618
safety instructions
GHS labeling of hazardous substances danger
H and P phrases	H: 301
	P: 301 + 330 + 331 + 310
Toxicological data	270 mg kg −1 ( LD 50 , mouse , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

1-Acetyl-2-phenylhydrazine is a chemical compound from the group of hydrazides and is a derivative (chemistry) of both phenylhydrazine and acetic acid .

properties

1-Acetyl-2-phenylhydrazine is a white solid.

use

1-Acetyl-2-phenylhydrazine is contained in superglues .

The compound can be used to induce hemolytic anemia for studies of the hematopoietic system as it forms free radicals with oxy hemoglobin . 1-Acetyl-2-phenylhydrazine is also used to trigger tumors.

Individual evidence

↑ Data sheet N-Acetyl-N′-phenylhydrazine, 98% from AlfaAesar, accessed on August 26, 2015 ( PDF )(JavaScript required) .
^ ^A ^b Carl L. Yaws: The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals Physical Properties for More Than 54,000 Organic and Inorganic Chemical Compounds, Coverage for C1 to C100 Organics and Ac to Zr Inorganics . Gulf Professional Publishing, 2015, ISBN 978-0-12-801146-1 , pp. 195 ( limited preview in Google Book search).
↑ ^a ^b ^c ^d Data sheet 1-Acetyl-2-phenylhydrazine, ≥98% from Sigma-Aldrich , accessed on August 26, 2015 ( PDF ).
↑ Entry on 1-Acetyl-2-phenylhydrazine at TCI Europe, accessed on August 26, 2015.
↑ ^a ^b Entry on 2′-phenylacetohydrazide in the GESTIS substance database of the IFA , accessed on January 8, 2018(JavaScript required) .
↑ z. B. BINDULIN
^ Paul J. Thornalley: The haemolytic reactions of 1-acetyl-2-phenylhydrazine and hydrazine: A spin trapping study . In: Chemico-Biological Interactions . tape 50 , no. 3 , August 1984, pp. 339-349 , doi : 10.1016 / 0009-2797 (84) 90041-3 .
↑ B. Toth: 1-Acetyl-2-phenylhydrazine carcinogenesis in mice. In: British Journal of Cancer . tape 39 , no. 5 , May 1979, pp. 584-587 , PMC 2009896 (free full text).

[Alfa-1] Data sheet N-Acetyl-N′-phenylhydrazine, 98% from AlfaAesar, accessed on August 26, 2015 ( PDF )(JavaScript required) .

[Carl_L._Yaws-2] A ^b Carl L. Yaws: The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals Physical Properties for More Than 54,000 Organic and Inorganic Chemical Compounds, Coverage for C1 to C100 Organics and Ac to Zr Inorganics . Gulf Professional Publishing, 2015, ISBN 978-0-12-801146-1 , pp. 195 ( limited preview in Google Book search).

[Sigma-3] Data sheet 1-Acetyl-2-phenylhydrazine, ≥98% from Sigma-Aldrich , accessed on August 26, 2015 ( PDF ).

[TCI-4] Entry on 1-Acetyl-2-phenylhydrazine at TCI Europe, accessed on August 26, 2015.

[GESTIS-5] Entry on 2′-phenylacetohydrazide in the GESTIS substance database of the IFA , accessed on January 8, 2018(JavaScript required) .

[6] z. B. BINDULIN

[7] Paul J. Thornalley: The haemolytic reactions of 1-acetyl-2-phenylhydrazine and hydrazine: A spin trapping study . In: Chemico-Biological Interactions . tape 50 , no. 3 , August 1984, pp. 339-349 , doi : 10.1016 / 0009-2797 (84) 90041-3 .

[8] B. Toth: 1-Acetyl-2-phenylhydrazine carcinogenesis in mice. In: British Journal of Cancer . tape 39 , no. 5 , May 1979, pp. 584-587 , PMC 2009896 (free full text).