2,2-diethyl-1,3-propanediol
Structural formula | ||||||||||||||||
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General | ||||||||||||||||
Surname | 2,2-diethyl-1,3-propanediol | |||||||||||||||
other names |
Prenderol |
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Molecular formula | C 7 H 16 O 2 | |||||||||||||||
Brief description |
yellowish solid |
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External identifiers / databases | ||||||||||||||||
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properties | ||||||||||||||||
Molar mass | 132.20 g mol −1 | |||||||||||||||
Physical state |
firmly |
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Melting point |
59-61 ° C |
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boiling point |
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solubility |
very soluble in water, diethyl ether and ethanol |
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Refractive index |
1.4574 (20 ° C) |
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safety instructions | ||||||||||||||||
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Toxicological data | ||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C |
2,2-Diethyl-1,3-propanediol is a chemical compound from the group of alkanediols .
properties
2,2-Diethyl-1,3-propanediol is a yellowish solid that is very soluble in water, diethyl ether and ethanol . The compound has a monoclinic crystal structure with the space group P 2 1 / c (space group no. 14) .
use
2,2-Diethyl-1,3-propanediol was previously used as a muscle relaxant under the name Prenderol. Later on, esters of the compound with a longer duration of action were developed.
Individual evidence
- ↑ a b c d e f g h data sheet 2,2-diethyl-1,3-propanediol, 99% from Sigma-Aldrich , accessed on December 3, 2018 ( PDF ).
- ↑ a b fishersci: Material Safety Data Sheet 2,2-Diethyl-1,3-propanediol, 99 +% , accessed on December 3, 2018
- ↑ a b W.LF Armarego: Purification of Laboratory Chemicals . Butterworth-Heinemann, 2017, ISBN 978-0-12-805456-7 , pp. 1138 ( limited preview in Google Book search).
- ↑ a b David R. Lide: CRC Handbook of Chemistry and Physics A Ready-reference Book of Chemical and Physical Data . CRC Press, 1995, ISBN 978-0-8493-0595-5 , pp. 188 ( limited preview in Google Book search).
- ^ University of Southampton: 2,2-diethyl-1,3-propanediol - eCrystals - University of Southampton , accessed December 3, 2018.
- ^ Basics and methods of clinical psychiatry . Springer-Verlag, 2013, ISBN 978-3-662-00726-6 , pp. 603 ( limited preview in Google Book search).
- ↑ J. Büchi: Fundamentals of drug research and synthetic drugs . Springer-Verlag, 2013, ISBN 978-3-0348-4019-4 , pp. 190 ( limited preview in Google Book Search).
- ↑ 3.0.CO; 2-A "> Audrey B. Mailer: Effects of mephenesin and prenderol on intellectual functions of mental patients. In: Journal of Clinical Psychology . 10, 1954, p. 283, doi : 10.1002 / 1097-4679 ( 195407) 10: 3 <283 :: AID-JCLP2270100322> 3.0.CO; 2-A .
- ↑ Irwin H. Slater, John P. O'Leary, EJ Pribyl: Some Attempts to Prolong the Duration of Action of 2,2-Diethyl-1,3-Propanediol (Prenderol). In: Journal of the American Pharmaceutical Association . 43, 1954, p. 547, doi : 10.1002 / jps.3030430909 .