Isopropyl 4-hydroxybenzoate

Structural formula
General
Surname	Isopropyl 4-hydroxybenzoate
other names	Isopropyl 4-hydroxybenzoate Isopropyl paraben
Molecular formula	C 10 H 12 O 3
Brief description	white solid
External identifiers / databases
CAS number 4191-73-5 EC number 224-069-3 ECHA InfoCard 100,021,882 PubChem 20161 ChemSpider 18995 Wikidata Q15426255
properties
Molar mass	180.20 g mol −1
Physical state	firmly
Melting point	84-87 ° C
boiling point	160 ° C (5 mmHg)
solubility	soluble in methanol soluble in chloroform and ethyl acetate
safety instructions
GHS labeling of hazardous substances danger H and P phrases H: 302 P: 280-301 + 312 + 330-305 + 351 + 338 + 310
Toxicological data	1900 mg kg −1 ( LD 50 ,  mouse ,  sc )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

4-Hydroxybenzoic acid isopropyl ester is a chemical compound from the group of parabens .

Extraction and presentation

The compound can be prepared by the stepwise addition of isopropanol and thionyl chloride to p -hydroxybenzoic acid at a low temperature, followed by heating the reaction mixture.

properties

Isopropyl 4-hydroxybenzoate is a white solid that is soluble in methanol.

use

Isopropyl 4-hydroxybenzoate is used as a preservative in cosmetics and food.

Individual evidence

1. ↑ ^{a b c d e f} data sheet isopropyl 4-hydroxybenzoate, analytical standard at Sigma-Aldrich , accessed on December 13, 2019 ( PDF ).
2. ↑ ^{a b c d} Entry on Isopropyl 4-Hydroxybenzoate at TCI Europe, accessed on December 13, 2019.
3. ↑ ^{a b} Data sheet isopropyl 4-hydroxybenzoate, 98% from AlfaAesar, accessed on December 13, 2019 ( PDF )(JavaScript required) .
4. ↑ Google Patents: CN103420841B - Preparation method of isopropyl p-hydroxybenzoate , accessed December 14, 2019.
5. ↑ Michael Ash: Handbook of Preservatives . Synapse Info Resources, 2004, ISBN 978-1-890595-66-1 , pp. 427 ( limited preview in Google Book search).