8-nitroquinoline

Structural formula
General
Surname	8-nitroquinoline
Molecular formula	C 9 H 6 N 2 O 2
Brief description	yellow solid
External identifiers / databases
CAS number 607-35-2 EC number 210-135-9 ECHA InfoCard 100.009.215 PubChem 11830 ChemSpider 11337 Wikidata Q270157
properties
Molar mass	174.16 g mol −1
Physical state	firmly
Melting point	86-88 ° C
safety instructions
GHS labeling of hazardous substances Caution H and P phrases H: 302-312-315-319-332-335-351 P: 261-280-305 + 351 + 338
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

8-Nitroquinoline is a heterocyclic chemical compound which consists of a quinoline skeleton with a nitro group in the 8-position .

presentation

8-Nitroquinoline can be made by nitrating quinoline. Electrophilic aromatic substitutions on quinoline occur fastest at the 5- and 8-positions. As a nitration mixture of equal parts of is 5 - and 8-nitroquinoline obtained while other isomers are formed only to a minor extent. The nitration of quinoline has a weaker selectivity than that of isoquinoline, in which almost exclusively 5-nitroisoquinoline is formed.

Individual evidence

1. ↑ ^{a b} Data sheet 8-nitroquinoline from AlfaAesar, accessed on July 18, 2010 ( PDF )(JavaScript required) .
2. ↑ ^{a b} Data sheet 8-Nitroquinoline from Sigma-Aldrich , accessed on March 18, 2011 ( PDF ).
3. ↑ MW Austin, JH Ridd: The kinetics and mechanism of heteroaromatic nitration. Part I. Quinoline , in: J. Chem. Soc. 1963 : 4204-4210; doi : 10.1039 / JR9630004204 .
4. ↑ JA Joules, K. Mills: Heterocyclic Chemistry , 5th Edition, pp. 177-199, Blackwell Publishing, Chichester, 2010, ISBN 978-1-4051-9365-8 .