Acetone oxime
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| General | ||||||||||||||||
| Surname | Acetone oxime | |||||||||||||||
| Molecular formula | C 3 H 7 NO | |||||||||||||||
| Brief description |
white, crystalline powder with a characteristic odor |
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| properties | ||||||||||||||||
| Molar mass | 73.09 g mol −1 | |||||||||||||||
| Physical state |
firmly |
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| density |
0.901 g cm −3 |
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| Melting point |
60 ° C |
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| boiling point |
135-136 ° C |
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| solubility |
easy in water (330 g l −1 at 20 ° C) |
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| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | ||||||||||||||||
Acetone oxime is a chemical compound from the group of oximes and the simplest representative of the ketoxime .
Extraction and presentation
Acetone oxime can be obtained by condensation of acetone with hydroxylamine under acid catalysis (pH = 4-5), usually using hydroxylamine hydrochloride .
properties
The heat of decomposition determined by DSC is −110 kJ · mol −1 or −1500 kJ · kg −1 .
use
The compound serves as a starting material in the Beckmann and Neber rearrangements .
safety instructions
Acetone oxime was included by the EU in 2015 in accordance with Regulation (EC) No. 1907/2006 (REACH) as part of substance evaluation in the Community's ongoing action plan ( CoRAP ). The effects of the substance on human health and the environment are re-evaluated and, if necessary, follow-up measures are initiated. Acetone oxime uptake was caused by concerns about environmental exposure, worker exposure , high risk characterization ratio (RCR) and widespread use, as well as the potential dangers of carcinogenic, mutagenic and sensitizing properties. The re-evaluation took place from 2016 and was carried out by Austria . A final report was then published.
Individual evidence
- ↑ a b c d e Entry on acetone oxime in the GESTIS substance database of the IFA , accessed on January 9, 2019(JavaScript required) .
- ↑ a b c d Entry on acetone oxime. In: Römpp Online . Georg Thieme Verlag, accessed on May 2, 2014.
- ↑ Grewer, T .; Klais, O .: Exothermic decomposition - investigations of the characteristic material properties , VDI-Verlag, series "Humanisierung des Arbeitsleben", Volume 84, Düsseldorf 1988, ISBN 3-18-400855-X , p. 9.
- ↑ European Chemicals Agency (ECHA): Substance Evaluation Conclusion and Evaluation Report .
- ↑ Community rolling action plan ( CoRAP ) of the European Chemicals Agency (ECHA): acetone oxime , accessed on March 26, 2019.