Hydroxylamine hydrochloride

Structural formula
General
Surname	Hydroxylamine hydrochloride
other names	Hydroxylammonium chloride; HACl;
Molecular formula	[NH 3 OH] Cl
Brief description	colorless crystals
External identifiers / databases
EC number	226-798-2
ECHA InfoCard	100.024.362
PubChem	443297
Wikidata	Q421356
properties
Molar mass	69.49 g mol −1
Physical state	firmly
density	1.67 g cm −3
Melting point	159 ° C (decomposition)
solubility	good in water (830 g l −1 at 20 ° C); soluble in ethanol ;
safety instructions
H and P phrases	H: 290-302 + 312-315-317-319-351-373-400
	P: 260-280-301 + 312 + 330-305 + 351 + 338
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Hydroxylamine hydrochloride , also known as hydroxylammonium chloride , is a colorless, crystalline inorganic chemical compound . It is the hydrochloric acid salt of hydroxylamine and behaves like unbound hydroxylamine in most chemical reactions , but is more thermally stable .

Manufacturing

Hydroxylamine hydrochloride is accessible through

Electrolysis of a mixture of mercury nitrate , sulfuric acid and nitric acid (this creates the sulfate) and subsequent addition of barium chloride solution .
by boiling potassium hydroxylamine disulfonate , forming the sulfate as above, from which the product with barium chloride is obtained.

{\ displaystyle \ mathrm {HON (SO_ {3} K) _ {2} +2 \ H_ {2} O \ longrightarrow (NH_ {3} OH) HSO_ {4} + K_ {2} SO_ {4}}}

properties

Hydroxylamine hydrochloride reacts with aldehydes or ketones to form oximes and with carboxylic acids to form hydroxamic acids .

use

Hydroxylamine hydrochloride is a versatile reagent in pharmaceutical and organic synthesis, for example for the synthesis of oximes and oxime ethers from carbonyl compounds or for the synthesis of hydroxamic acids. In analysis it is used in oxime titration .

Legal status

In Germany, hydroxylamine hydrochloride is classified as an explosive substance of substance group C in accordance with the regulations of the Explosives Act.

literature

Entry on hydroxylammonium chloride. In: Römpp Online . Georg Thieme Verlag, accessed on July 15, 2014.

Individual evidence

↑ ^a ^b entry on hydroxylammonium chloride. In: Römpp Online . Georg Thieme Verlag, accessed on July 15, 2014.
↑ ^a ^b ^c ^d ^e Entry on hydroxylammonium chloride in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .
↑ Entry on Hydroxylammonium chloride in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ G. Brauer (Ed.), Handbook of Preparative Inorganic Chemistry 2nd ed., Vol. 1, Academic Press 1963, pp. 487-8.
↑ Announcement of the new findings made by BAM since 1987 in accordance with Section 2 SprengG . (PDF)

[roempp-1] try on hydroxylammonium chloride. In: Römpp Online . Georg Thieme Verlag, accessed on July 15, 2014.

[GESTIS-2] Entry on hydroxylammonium chloride in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .

[CLP_100.024.362-3] Entry on Hydroxylammonium chloride in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[4] G. Brauer (Ed.), Handbook of Preparative Inorganic Chemistry 2nd ed., Vol. 1, Academic Press 1963, pp. 487-8.

[5] Announcement of the new findings made by BAM since 1987 in accordance with Section 2 SprengG . (PDF)