Androsterone

Structural formula
General
Non-proprietary name	Androsterone
other names	3 α - hydroxy- 5 α -androstan-17-one
Molecular formula	C 19 H 30 O 2
External identifiers / databases
CAS number 53-41-8 EC number 200-173-4 ECHA InfoCard 100,000,159 PubChem 5879 ChemSpider 5668 Wikidata Q422469
properties
Molar mass	290.44 g · mol -1
Physical state	firmly
Melting point	185-185.5 ° C
solubility	Hardly soluble in water, soluble in most organic solvents
safety instructions
GHS labeling of hazardous substances danger H and P phrases H: 315-319-334-335 P: 261-305 + 351 + 338-342 + 311
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Androsterone (ADT) is an androgen (male sex hormone ). It is a metabolite of the sex hormone testosterone with weak androgenic activity and is formed in the liver . Androsterone, like testosterone, regulates the sexual drive and is important for the development of male secondary sexual characteristics.

Androsterone was the first isolated steroid hormone . It was found in male urine in 1931 by Adolf Butenandt and Kurt Tscherning . To do this, they distilled 25,000 liters and extracted 50 milligrams of crystalline androsterone from it.

Web links

Wiktionary: Androsterone  - explanations of meanings, word origins, synonyms, translations

• KEGG : Androsterone

Individual evidence

1. ↑ ^{a b} The Merck Index . An Encyclopaedia of Chemicals, Drugs and Biologicals . 14th edition, 2006, pp. 103-104, ISBN 978-0-911910-00-1 .
2. ↑ ^{a b} data sheet androsterone from Sigma-Aldrich , accessed on March 9, 2011 ( PDF ).
3. ↑ Butenandt, A. & Tscherning, K. (1934): About Androsteron, a crystallized male sex hormone. I Isolation and purification from male urine. In: Z. Physiol. Chem. Vol. 229, pp. 167-184.