Arabinosyl nucleosides
Arabinosyl nucleosides are derivatives of nucleosides . They contain - in contrast to most nucleosides - instead of β- D -Ribofuranose the β- D -Arabinofuranose . They are mostly used as cytostatics or virostatics .
| Nucleobase | (Ribosyl) nucleoside | Arabinosyl nucleoside |
|---|---|---|
|
|
|
| Cytosine | Cytidine , C. | Cytarabine , araC |
|
|
|
| Adenine | Adenosine , A. | Vidarabine , araA |
Further examples
literature
- Priscilla J. Ortiz, Marion J. Manduka, Seymour S. Cohen: The Lethality of Some D-Arabinosyl Nucleotides to Mouse Fibroblasts , Cancer Res , 1972 , 32 , pp. 1512-1517 ( PMID 4260553 ).
- Werner E. Müller: Rational design of arabinosyl nucleosides as antitumor and antiviral agents , Jpn J Antibiot , 1977 Dec, 30 Suppl., Pp. 104-120 ( PMID 612702 ).
Web links
Commons : Nucleosides - Collection of images, videos and audio files
