Intervertebral disc

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Intervertebral disc in humans

The intervertebral disc or intervertebral disc ( latin intervertebral disc ) is a flexible, faserknorplige formation, each of the vertebral bodies of two adjacent vertebrae in the area between the second cervical vertebra and the sacrum connects. They form a cartilaginous structure ( synchondrosis ) between the vertebral bodies. There are no intervertebral discs between the skull and the first cervical vertebra and between the first and second cervical vertebrae. The spine of the people has 23 intervertebral discs. They make up about 25 percent of the total length of the spine. Their height and area increases towards the sacrum. The number of intervertebral discs in other mammals varies with the number of vertebrae.


The average height of the intervertebral discs in the cervical spine is around 3 mm, in the thoracic spine around 5 mm and in the lumbar spine around 7 mm high. They are wedge-shaped, corresponding to the curvature of the human spine, they are thicker in the area of ​​the cervical and lumbar lordosis in the front and thicker in the area of ​​the chest kyphosis in the back.

Herniated disc , the herniated nucleus presses on the ventral root (anterior root) of the spinal nerve 1 spinal cord , 2 dorsal roots , 3 spinal ganglion , 4 ventral roots, 5 spinal nerves , 6 + 7 intervertebral discs: 6 fibrous ring, 7 gelatinous nucleus , 8 vertebral bodies

Intervertebral discs consist of two parts:

  • Anulus fibrosus (outer ring of fibers)
  • Nucleus pulposus (inner gelatinous nucleus )

The annulus fibrosus , the fibrous ring of the intervertebral disc, consists of concentric layers of collagenous connective tissue fibers (outer zone), which gradually merge inward into fiber cartilage (inner zone). The fibers, which predominantly consist of type 1 collagen , have opposite angles of inclination. The intersecting connective tissue fibers of the outer zone attach to the marginal ridges of the vertebral bodies.

The nucleus pulposus is a cell-poor gelatinous tissue that contains 80–85% water. It contains few fibroblasts and type 2 collagen. Due to the high proportion of glycosaminoglycans ( chondroitin sulfate , keratan sulfate ), water is reversibly bound, so that the nucleus, like a pillow of water, is not compressible but can be deformed. The gelatinous nucleus is located at the position of the original segment of the notochord , but the tissue does not derive directly from it. According to another view, the nucleus gelatinous represents a remnant of the notochord.

Under constant load, the gelatinous nuclei lose fluid reversibly and thus lose height. As a result, a person can lose up to 1 to 2 cm in body height, including the arch of the foot even up to 3 cm. In the relieved state, the gelatinous nuclei absorb fluid again. This absorption and decrease of water is also the only way by which the intervertebral discs are supplied with nutrients, since after the age of 20 they no longer have any blood vessels when they have finished growing . The change in pressure between loading and unloading is a basic requirement for the metabolism of the intervertebral discs.


The intervertebral disc serves as an elastic pressure pad and allows the spine to move. The spinal column sections are all the more mobile, the greater the ratio of intervertebral disc to vertebral body height. In the area of ​​the cervical spine the ratio is highest with 2: 5, in the area of ​​the lumbar spine with 1: 3 in the middle area and in the area of ​​the thoracic spine with 1: 5 lowest. The intervertebral discs distribute the forces acting on the spine evenly over the entire end plate of the vertebra. The gelatinous core absorbs around 75% and the fiber ring 25% of the forces. A young person's intervertebral disc can withstand forces of up to 800 N / m 2 . The intervertebral disc is elastically deformed by eccentric loading, whereby the gelatinous core is shifted to the less loaded side. The fiber architecture of the fiber ring limits the circumference between the vertebrae and, in particular, counteracts twisting. The swelling pressure of the gelatinous nuclei also keeps the anterior and posterior longitudinal ligament under tension and thereby supports their braking effect.

Clinical Aspects

If there is a structural disorder of the cover plates during growth, material of the intervertebral disc can penetrate into the cancellous bone of the vertebral body (Schmorl nodules in Scheuermann's disease ). From the age of 30, degenerative processes lead to a change in the composition of the matrix and thus to reduced water retention. This results in cracks and crevices which, when subjected to pressure, can lead to bulging or even to the passage of material of the gelatinous nucleus through the annulus fibrosus. This is known as disc protrusion or herniated disc . The wear and tear of the intervertebral disc leads to reactive changes in the bone tissue of the adjacent vertebrae ( osteochondrosis intervertebralis , spondylosis deformans ).

The surgical removal of a herniated disc is known as nucleotomy , the removal of the entire disc with osseous stiffening and fusion of the adjacent vertebral bodies is called spondylodesis . In addition, the cervical and lumbar spine can be replaced by an intervertebral disc prosthesis .

Web links

Wiktionary: intervertebral disc  - explanations of meanings, word origins, synonyms, translations
Commons : intervertebral disc  - collection of images, videos and audio files

Individual evidence

  1. ^ Theodor H. Schiebler, Walter Schmidt: Anatomy: cytology, histology, history of development, macroscopic and microscopic human anatomy . 5th edition. Springer, Berlin 2013, ISBN 978-3-662-05733-9 , pp. 143 .
  2. a b c d e f Michael Schünke: Anatomy - topography and function of the movement system . Georg Thieme, Stuttgart 2000, ISBN 978-3-13-118571-6 , p. 134-136 .
  3. a b c d Walther Graumann: Compact textbook anatomy . tape 2 . Schattauer, Stuttgart 2004, ISBN 978-3-7945-2062-6 , pp. 10-11 .
  4. ^ Theodor H. Schiebler, Walter Schmidt: Anatomy: cytology, histology, history of development, macroscopic and microscopic human anatomy . 5th edition. Springer, Berlin 2013, ISBN 978-3-662-05733-9 , pp. 215 .
  5. Techniker Krankenkasse: A healthy back needs properly functioning intervertebral discs
  6. Rolf Wirhed: Sports anatomy and kinesiology . Schattauer, Stuttgart 2001, ISBN 978-3-7945-2081-7 , pp. 72 .