Benomyl

Structural formula
General
Surname	Benomyl
other names	Methyl 1- (butylcarbamoyl) benzimidazol-2-ylcarbamate
Molecular formula	C 14 H 18 N 4 O 3
Brief description	yellow-brown powder with a faint odor
External identifiers / databases
CAS number 17804-35-2 EC number 241-775-7 ECHA InfoCard 100,037,962 PubChem 28780 Wikidata Q420172
properties
Molar mass	290.32 g · mol -1
Physical state	firmly
density	0.38 g cm −3
Melting point	Decomposition at 140 ° C
solubility	almost insoluble in water (2.9 mg l −1 at 25 ° C)
safety instructions
GHS hazard labeling from  Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary danger H and P phrases H: 315-317-335-340-360FD-410 P: 201-261-273-280-308 + 313-501
MAK	Switzerland: 0.8 ml m −3 or 10 mg m −3 (measured as inhalable dust )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Benomyl is a fungicide that binds to microtubules . This means that important processes such as intracellular transport and cell division can no longer take place. Benomyl prefers fungal microtubules over those of animals.

Benomyl was developed by DuPont in 1968 . Resistance emerged as early as the 1970s.

Admission

In the EU states including Germany and Austria as well as in Switzerland no pesticides with this active substance are permitted. The last approvals expired in 2003.

Benomyl decision

After the catastrophic crop failures in 1974, a farmer from Altland sued the DuPont concern. In the Apple Scab II decision of March 17, 1981, the Federal Court of Justice ruled that there was a product manufacturer's obligation to monitor products after the product had been placed on the market.

Individual evidence

1. ↑ ^{a b c d e} Entry on Benomyl in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .
2. ↑ Entry on Benomyl in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
3. ↑ Benomyl data sheet at Sigma-Aldrich , accessed on May 15, 2017 ( PDF ).
4. ↑ Swiss Accident Insurance Fund (Suva): Limit values ​​- current MAK and BAT values (search for 17804-35-2 or Benomyl ), accessed on November 2, 2015.
5. ^ Directorate-General for Health and Food Safety of the European Commission: Entry on Benomyl in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 11, 2016.
6. ↑ Georg Meinert (Badische Bauern Zeitung): 320 existing active ingredients will disappear from the EU-wide market in 2003 on December 21, 2002, accessed on June 14, 2013.
7. ↑ Thomas Winkelmann: Product liability in international corporate cooperation . Duncker & Humblot, 1991, pp. 155 ( limited preview in Google Book search).
8. ↑ net4lawyer & openlaw: Apple scab case ( Memento from August 8, 2014 in the Internet Archive )