Brilliant blue FCF

Structural formula
General
Surname	Brilliant blue FCF
other names	Disodium 2 - [( Z ) - {4- [ethyl (3-sulfonatobenzyl) amino] phenyl} {(4 Z ) -4- [ethyl (3-sulfonatobenzyl) iminio] -2,5-cyclohexadien-1-ylidene } methyl] benzenesulfonate ( IUPAC ) ; CI Acid Blue 9; CI 42090; CI Food Blue 2; E 133 ; Patent blue AE; Amido blue AE; Erioglaucin A; ACID BLUE 9 ( INCI ) ;
Molecular formula	C 37 H 34 N 2 Na 2 O 9 S 3
Brief description	finely crystalline, dark purple powder
External identifiers / databases
EC number	223-339-8
ECHA InfoCard	100.021.219
PubChem	19700
ChemSpider	18556
Wikidata	Q420093
properties
Molar mass	792.85 g mol −1
Physical state	firmly
safety instructions
GHS labeling of hazardous substances	no GHS pictograms
	no GHS pictograms
H and P phrases	H: 412
	P: 273
Toxicological data	4600 mg kg −1 ( LD 50 , mouse , sc )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Brilliant blue FCF ( E 133) is a blue triphenylmethane dye that is used as a food coloring . It belongs to the application group of acid dyes and is one of the patent blue dyes .

properties

Brillantblau FCF is a reddish-blue powder, water-soluble and stable. As the pH value falls, the dye decomposes, which shortens the π-electron system that provides the color . This changes the color from blue first to green and then to yellow. If the pH value drops even further, brilliant blue is completely discolored. The neutral solution has an absorption maximum at λ _max. = 630 nm.

Manufacturing

Brilliant blue FCF is made from 2-sulfobenzaldehyde and 3 - {[ethyl (phenyl) amino] methyl} benzenesulfonic acid:

The disodium salt is commercially available. The calcium, ammonium and potassium salts as well as the aluminum varnish of the dye are also permitted.

use

Use in the Blue Curaçao

Brillantblau FCF is used to color drinks, food and medicines, as well as in liquid surfactant products (liquid detergents , fabric softeners ) and in mouthwash , gel toothpaste and perfumes.

In order to achieve green, purple or brown tones, brilliant blue FCF is mixed with other dyes, e.g. B. with tartrazine (E 102) to create green tones.

health

Brilliant blue FCF is considered harmless. The permitted daily dose was set at 6 mg / kg body weight. Most of the dye is excreted unchanged.

Animal experiments have shown that brilliant blue FCF is deposited in the kidneys and lymph vessels when taken in high doses .

Legal situation

Brilliant blue FCF is only approved for certain products. These include:

edible coatings for cheese and sausage ( qs )
Sweets (max. 300 mg / kg)
Cakes, biscuits, pastries (max. 200 mg / kg)
Spirits, fruit and fruit wines (max. 200 mg / kg)
Ice cream, desserts (max. 150 mg / kg)
Sauces, condiments, appetizers (max. 500 mg / kg)
alcoholic and non-alcoholic beverages

Individual evidence

↑ Entry on E 133: Brilliant Blue FCF in the European database for food additives, accessed on June 16, 2020.

^ Entry on ACID BLUE 9 in the CosIng database of the EU Commission, accessed on April 27, 2020.

↑ Data sheet Brillantblau FCF from Acros, accessed on February 20, 2010.

↑ ^a ^b Data sheet Erioglaucine disodium salt from Sigma-Aldrich , accessed on May 20, 2017 ( PDF ).

^ Entry on brilliant blue FCF in the ChemIDplus database of the United States National Library of Medicine (NLM) .

^ Journal of Cancer Research . Vol. 64, pp. 287, 1961.

↑ External identifiers or database links for BrilliantBlue FCF Ammonium : CAS number: 2650-18-2, EC number: 220-168-0, ECHA InfoCard: 100.018.335 , PubChem : 118705701 , ChemSpider : 16602 , Wikidata : Q27269761 .

↑ External identifiers or database links for brilliant blue FCF potassium : CAS number: 71701-18-3, PubChem : 101533083 , ChemSpider : 150983 , Wikidata : Q82982410 .