Carmen Buchrieser

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Carmen Buchrieser (born August 6, 1961 in Graz , Austria ) is an Austrian biologist and university professor at the Pasteur Institute in Paris (France).

Career

Buchrieser studied biology at the University of Graz and received his doctorate in microbiology from the University of Salzburg in 1986 . She then did research for several years at the Hygiene Institute of the University of Graz in Austria, at the Listeria Laboratory and at the Yersinia Laboratory of the Institut Pasteur in Paris in France and at the Food Research Institute of the University of Wisconsin – Madison in the USA. In 2000 she moved to the Pasteur Institute as an assistant professor and became an associate professor in 2005.

Since 2008 she has been the head of the “Biology of Intracellular Bacteria” department and since 2014 she has also been a professor at the Pasteur Institute. Since 2013 she has been a member of the Scientific Council of the Pasteur Institute.

In 2014 she spent research stays at the Institute for Microbiology at the University of Greifswald and at the Max Planck Institute for Infection Biology in Berlin as a fellow of the Humboldt Foundation .

research

Buchrieser deals with pathogenic bacteria , her focus is on Listeria , Yersinia and Legionella . You will learn about the genetic factors of bacterial pathogenicity , how they change over time and across different bacterial strains and what mechanisms they can use to deal with the human immune system .

By comparing the genome sequences of Listeria monocytogenes with the non-pathogenic strain Listeria innocua , she was able to show the strategies with which Listeria adapt to their environment and how the pathogenicity was driven by the uptake and deletion of genes .

For Legionella pneumophila , the bacterium that causes Legionnaires' disease, Buchrieser was able to show how the bacterium can imitate host proteins and thus hide from the immune response (" molecular mimicry ").

For mycobacteria , she developed a new hypothesis of the evolution of the various strains. Based on genetic ancestry analyzes, she was able to show that the human pathogenic Mycobacterium tuberculosis does not descend from Mycobacterium bovis , the causative agent of bovine tuberculosis, but has a different human pathogenic ancestor.

Awards

Web links

Individual evidence

  1. ^ Scientific Council. November 17, 2016, accessed May 23, 2020 (UK English).
  2. ↑ R. Schoenfeld: Lysergic acid diethylamide- and mescaline-induced attenuation of the effect of punishment in the rat. In: Science. 192, 1976, p. 801, doi : 10.1126 / science.1063447 .
  3. ↑ Tamara Nora, Mariella Lomma, Laura Gomez-Valero, Carmen Buchrieser: Molecular mimicry: an important virulence strategy employed by to subvert host functions. In: Future Microbiology. 4, 2009, p. 691, doi : 10.2217 / fmb.09.47 .
  4. ↑ R. Brosch, SV Gordon, M. Marmiesse, P. Brodin, C. Buchrieser, K. Eiglmeier, T. Garnier, C. Gutierrez, G. Hewinson, K. Kremer, LM Parsons, AS Pym, S. Samper, D. van Soolingen, ST Cole: A new evolutionary scenario for the complex. In: Proceedings of the National Academy of Sciences. 99, 2002, p. 3684, doi : 10.1073 / pnas.052548299 .
  5. ↑ research pasteur fr-Institut Pasteur: Carmen Buchrieser receives the 2019 Jacques Piraud Award | Research Institute Pasteur. Retrieved March 23, 2020 (American English).
  6. ↑ Carmen Buchrieser. Leopoldina - National Academy of Sciences, accessed on March 23, 2020 .


personal data
SURNAME Buchrieser, Carmen
BRIEF DESCRIPTION Austrian biologist and university professor
DATE OF BIRTH August 6, 1961
PLACE OF BIRTH Graz