The Chapare virus ( CHAV , officially Chapare mammarenavirus ) is an enveloped virus with a single-stranded, ambisense RNA as genome , which is present in the virion in two closed rings (L and S segment) . The virus causes hemorrhagic fever with an incubation period of around 14 days. The spread of the virus is still unclear and, as with the closely related viruses, rodents are very likely to serve as carriers .
The Chapare virus was first described in 2008. It was first found in the blood serum of a patient who died during an accumulation of severe hemorrhagic fever that occurred in December 2003 and January 2004 in the Bolivian province of Chapare . The virus was first identified serologically as arenavirus (today's name: Mammarenavirus ) and the genome sequence was clarified. The Chapare virus was then also detected in another patient who survived the local outbreak .
literature
S. Delgado, BR Erickson et al .: Chapare virus, a newly discovered arenavirus isolated from a fatal hemorrhagic fever case in Bolivia . PLoS Pathog . (2008) 4 (4) (E-Pub: e1000047) PMID 18421377
