Coumatetralyl
Structural formula | ||||||||||||||||
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General | ||||||||||||||||
Surname | Coumatetralyl | |||||||||||||||
other names |
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Molecular formula | C 19 H 16 O 3 | |||||||||||||||
Brief description |
colorless solid |
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properties | ||||||||||||||||
Molar mass | 292.33 g mol −1 | |||||||||||||||
Physical state |
firmly |
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Melting point |
172 ° C (decomposition) |
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solubility |
practically insoluble in water (425 mg l −1 at pH 7 and 20 ° C) |
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safety instructions | ||||||||||||||||
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Toxicological data | ||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Coumatetralyl is a chemical compound from the group of 4-hydroxycoumarins .
Extraction and presentation
Coumatetralyl can be obtained by reacting 4-hydroxycoumarin with 1-tetralol .
properties
Coumatetralyl is a flammable colorless solid which is practically insoluble in water. It decomposes at temperatures above 172 ° C.
use
Coumatetralyl is used as a rat and mouse control agent ( rodenticide ). It belongs to the same group as warfarin and is a first generation anticoagulant . This means that the substance prevents blood clotting, so that the target organism dies of internal bleeding 5 to 10 days after ingesting the active substance.
Admission
With the exception of rodenticides, no plant protection products containing coumatetralyl as an active ingredient are permitted in EU countries such as Germany, Austria or Switzerland.
Trade names
Racumin, Raukumin 57, Rodentin
Web links
- T. Grobosch, B. Angelow, D. Lampe: Acute intoxication with coumatetralyl - simultaneous determination of 5 superwarfarines and 5 other vitamin K antagonists in human serum using LC-ESI-MS. (PDF; 315 kB) In: T + K (2005) 72 (1): 46
- DIRECTIVE 85/2009 / EC OF THE COMMISSION of 29 July 2009 amending Directive 98/8 / EC of the European Parliament and of the Council to include the active substance coumatetralyl in Annex I (PDF)
Individual evidence
- ↑ a b Coumatetralyl data sheet from Sigma-Aldrich , accessed on February 15, 2017 ( PDF ).
- ↑ a b c d e f Entry on Coumatetralyl in the GESTIS substance database of the IFA , accessed on January 10, 2017(JavaScript required) .
- ↑ Entry on Coumatetralyl in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
- ↑ Thomas A. Unger: Pesticide synthesis handbook . 1996, ISBN 978-0-8155-1401-5 ( page 847 in the Google book search).
- ↑ Federal Institute for Occupational Safety and Health: Coumatetralyl ( Memento from June 23, 2013 in the Internet Archive ), June 3, 2010.
- ↑ General Directorate Health and Food Safety of the European Commission: Entry on Coumatetralyl in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; Retrieved March 3, 2016.