Demephion

Demephion is a mixture of two chemical compounds (Demephion-S and Demephion-O) from the group of thiophosphoric acid esters . During production, both isomers (the thione and thiol isomer) are formed at the same time.

Isomers of Demephion
Surname	Demephion-O	Demephion-S
other names	O , O -dimethyl- O -2-ethyl mercaptomethyl thionophosphate	O , O -dimethyl- S - (2-methylthioethyl) thiophosphate
	Tinox Cymetox Methyl demetone methyl
Structural formula
CAS number	682-80-4	2587-90-8
	8065-62-1 (mixture)
EC number	211-666-9	219-971-9
	693-045-6 (mixture)
ECHA info card	100.010.607	100.018.157
	100.221.416 (mixture)
PubChem	-	17423
	- (mixture)
Wikidata	Q15722789	Q15722731
	Q5255155 (mixture)
Molecular formula	C 5 H 13 O 3 PS 2
Molar mass	216.27 g mol −1
Physical state	liquid
density		1.218 g cm −3
Refractive index		1.508 (25 ° C)
GHS labeling	from  Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary danger	from  Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary danger
H and P phrases	300-311	300-311
	no EUH phrases	no EUH phrases
	?	?
Toxicological data		20 mg kg −1 ( LD 50 ,  rat ,  oral ) 68 mg kg −1 ( LD 50 ,  rat ,  transdermal )

use

Demephion has been used as an insecticide since 1955 and was approved in the GDR until 1979. In Germany, Austria and Switzerland, no pesticides with this active ingredient are permitted.

Individual evidence

1. ↑ ^{a b c d} Entry on Demephion-S in the GESTIS substance database of the IFA , accessed on December 29, 2019(JavaScript required) .
2. ↑ ^{a b} Entry on Demephion-O in the GESTIS substance database of the IFA , accessed on December 29, 2019(JavaScript required) .
3. ^ ^{A b} R. Edmundson: Dictionary of Organophosphorus Compounds . CRC Press, 1987, ISBN 978-0-412-25790-2 , pp. 188 ( limited preview in Google Book search).
4. ↑ Entry on Demephion-O in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on December 29, 2019. Manufacturers or distributors can expand the harmonized classification and labeling .
5. ↑ Entry on Demephion-S in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on December 29, 2019. Manufacturers or distributors can expand the harmonized classification and labeling .
6. ↑ herts.ac.uk: Demephion , accessed September 16, 2016.
7. ^ Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 18, 2016.