Dennis J. Slamon
Dennis Joseph Slamon (born August 6, 1948 in New Castle , Pennsylvania ) is an American oncologist and professor at the University of California, Los Angeles .
Life
Slamon earned a bachelor's degree in biology from Washington & Jefferson College in Washington , Pennsylvania in 1970 and an MD from the University of Chicago in Chicago , Illinois in 1975 , and Ph.D. from Winston Anderson and Werner Kirsten. in cell biology . From 1975 to 1978 Slamon worked as an assistant doctor at the University of Chicago Hospitals and Clinics , from 1978 to 1979 as chief resident . In 1978 he acquired the specialist for internal medicine ( internist ), in 1982 as a specialist in oncology . Since 1979 Slamon has been working in the hematology / oncology department at the University of California, Los Angeles School of Medicine , first as a fellow , then as a professor (1982 Adjunct Assistant Professor , 1984 Assistant Professor , 1988 Associate Professor , 1993 Full Professor).
Since 2013 Thomson Reuters has counted him among the favorites for a Nobel Prize ( Thomson Reuters Citation Laureates ) due to the number of his citations .
Slamon is married.
Act
Slamon's most important works concern the HER2 / neu receptor, an epidermal growth factor receptor that is found strongly on the tumor cells of around 20% of breast cancer patients , and the monoclonal antibody trastuzumab (trade name Herceptin), which is directed against HER2 / neu, which stimulates the growth of these Inhibits cells. Slamon's work is a particularly important example of the rapid clinical application of the results of basic research . Herceptin represents a paradigm shift in cancer therapy in that for the first time a chemotherapeutic agent could be developed specifically against specific properties of certain subgroups of tumors.
Slamon's life and his efforts to research the HER2 / neu receptor and the possibility of treatment with Herceptin were filmed in the 2008 television film Living proof with Harry Connick junior in the lead role.
Awards (selection)
- 2002 Gabbay Award
- 2004 Medal of Honor for Clinical Research of the American Cancer Society
- 2006 David A Karnofsky Memorial Award from the American Society of Clinical Oncology
- 2006 Warren Alpert Foundation Prize
- 2007 Gairdner Foundation International Award
- 2019 Sjöberg Prize
- 2019 Lasker ~ DeBakey Clinical Medical Research Award
literature
- Who's Who in America. 66th Edition, 2012, Volume 2: M – Z. Marquis Who's Who, Berkeley Heights 2011, ISBN 978-0-8379-7032-5 (Volume 2), ISBN 978-0-8379-7035-6 (Complete Works ), ISSN 0083-9396 , p. 4152
Web links
- Dennis Slamon, Director, Clinical / Translational Research and biography at the Jonsson Comprehensive Cancer Center of the University of California, Los Angeles ; accessed on February 6, 2016
- Curriculum Vitae (PDF, 483 kB) at oncologyinsights.com; Retrieved June 9, 2011
- Wendy Soderburg: Clearing a path to cancer cures. In: UCLA Today, March 24, 2009 ; Retrieved June 9, 2011
Individual evidence
- ↑ 2013 Predictions at Thomson Reuters (sciencewatch.com); Retrieved September 25, 2013
- ↑ Living Proof in the Internet Movie Database (English)
- ↑ American Cancer Society Presents 2004 Medal of Honor Awards ( Memento of the original from November 10, 2011 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. at charitywire.com; Retrieved June 9, 2011
- ↑ Oncology Luminary: Dr. Dennis Slamon - CancerProgress.Net. In: cancerprogress.net. September 29, 2014, accessed February 6, 2016 .
- ^ Dennis J. Slamon MD, PhD at the Gairdner Foundation ; Retrieved December 15, 2012
personal data | |
---|---|
SURNAME | Slamon, Dennis J. |
ALTERNATIVE NAMES | Slamon, Dennis Joseph (full name); Slamon, Dennis |
BRIEF DESCRIPTION | American oncologist |
DATE OF BIRTH | August 6, 1948 |
PLACE OF BIRTH | New Castle , Pennsylvania |