Deoxyguanosine

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Structural formula
Structural formula of deoxyguanosine
General
Surname Deoxyguanosine
other names
  • dG (short code)
  • 2'-deoxyguanosine
  • 9-β- D -deoxyribofuranosylguanine
  • 9 - [(2 R , 4 S , 5 R ) -4-hydroxy-5- (hydroxymethyl) oxolan-2-yl] -2-amino-1 H -purin-6-one
  • DEOXY GUANOSINE ( INCI )
Molecular formula C 10 H 13 N 5 O 4
Brief description

colorless solid

External identifiers / databases
CAS number
EC number 213-505-8
ECHA InfoCard 100.012.278
PubChem 135398592
ChemSpider 163230
Wikidata Q422488
properties
Molar mass 267.24 g mol −1
Physical state

firmly

solubility

50 mg / ml in 1 M ammonia solution

safety instructions
GHS labeling of hazardous substances
07 - Warning

Caution

H and P phrases H: 302
P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Deoxyguanosine (short dG or DNA sequences only G ) is a nucleoside and consists of the nucleobase guanine and sugar β- D -Desoxyribose .

Deoxyguanosine is part of deoxyribonucleic acid (DNA) and forms a base pair with deoxycytidine . The analog with ribose is guanosine .

Structural formula of a GC base pair

It can also form the structure of G-quadruplexes , which is particularly important for telomeres . Four dG lie in one plane and are connected via hydrogen bonds .

Individual evidence

  1. Entry on DEOXYGUANOSINE in the CosIng database of the EU Commission, accessed on March 30, 2020.
  2. Data sheet 2′-Deoxyguanosine monohydrate from Sigma-Aldrich , accessed on November 5, 2016 ( PDF ).
  3. a b c Data sheet Deoxyguanosine (monohydrate) from Sigma-Aldrich , accessed on November 5, 2016 ( PDF ).