Edward C. Taylor

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Edward Curtis Taylor Jr. (born August 3, 1923 in Springfield , Massachusetts - † November 22, 2017 in Saint Paul , Minnesota ) was an American chemist and former professor at Princeton University . He dealt with organic synthesis and is known for developing cytostatics .

Life

Taylor studied chemistry at Cornell University with a bachelor's degree in 1946 and a doctorate in 1949 with Cornelius Cain (An investigation of some aspects of the chemistry of the pteridines). As a post-doctoral student he was with Leopold Ružička at the ETH Zurich and in 1950/51 at the University of Illinois , where he also became a member of the faculty. From 1954 he was at Princeton University, from 1966 as A. Barton Hepburn Professor of Organic Chemistry .

He was visiting professor a. a. at Harvard, Freiburg, Stuttgart, at the University of Buffalo, in Groningen, Norwich and at the Weizmann Institute . He was on the editorial board of the Journal of Medicinal Chemistry and the Journal of Organic Chemistry , headed the Organic Chemistry Section of ACS in 1976/77 and was a chemical advisor to the Cancer Chemotherapy National Service Center . In 1968 he received an honorary doctorate from Hamilton College , which named its new science building after him in 2011. Taylor was a Guggenheim Fellow and received the Humboldt Research Award . In 1974 he received the American Chemical Society Award for Creative Work in Synthetic Organic Chemistry and in 1994 the Arthur C. Cope Scholar Award from ACS.

Taylor studied organic synthesis and methodology, chemistry of natural products and heterocycles (such as pteridines ), organic thallium chemistry, and medicinal chemistry. He has published over 450 papers and holds 52 US patents.

For the development of pemetrexed (trade name Alimta) with chemists at Eli Lilly , a folic acid antagonist used as a chemotherapeutic agent against various forms of cancer, he received the NAS Award for Chemistry in Service to Society in 2013 and the Thomas Alva Edison Award in 2004. The patent proceeds from Alimta enabled Princeton University to fully finance a spacious new chemistry building. He and his colleagues had previously developed the folic acid antagonist DDATHF (iometrexol).

He was a Fellow of the American Institute of Chemists , the New York Academy of Sciences, and the American Association for the Advancement of Science . In 2006 the ACS awarded him the Hero of Chemistry award.

Fonts

With Arnold Weisgerber , he has been editor of The Chemistry of Heterocyclic Compounds (Wiley-Interscience, from 1998 with Peter Wipf ) since 1968 and he is editor of General Heterocyclic Chemistry , Advances in Organic Chemistry . He wrote a series of educational films, Course on Principles of Heterocyclic Chemistry (American Chemical Society).

  • Editor with Wolfgang Pfleiderer : Pteridine Chemistry, Pergamon Press 1964
  • with Alexander McKillop: The Chemistry of Enaminonitriles and o-Aminonitriles, Interscience, 1970

Web links

Individual evidence

  1. ↑ Karin Dienst: Princeton chemist Edward C. Taylor, inventor of anti-cancer drug, dies at 94. Princeton University, November 29, 2017, accessed on December 3, 2017 (English).
  2. ↑ biographical data, publications and Academic pedigree of Edward Curtis Taylor, Jr. at academictree.org, accessed on 31 December 2017th
personal data
SURNAME Taylor, Edward C.
ALTERNATIVE NAMES Taylor, Edward Curtis (full name)
BRIEF DESCRIPTION American chemist
DATE OF BIRTH August 3, 1923
PLACE OF BIRTH Springfield , Massachusetts
DATE OF DEATH 22nd November 2017
Place of death Saint Paul , Minnesota