Hereditary tumor diseases are dealt with in the literature under different keywords. The frequently used term familial cancer syndromes should be introduced here for the time being.
Familial cancer syndromes make up about 1–2% of malignant tumors. So far, 20 hereditary cancer syndromes have been genetically characterized. The retinoblastoma was the first to be analyzed in this group. The starting point of the molecular dissection in this case was a deletion on chromosome 13 . The hereditary tumor genes are usually cancer genes with a dominant effect.
Christoph Wagener: Molecular Oncology. Thieme Verlag, Stuttgart 1999, ISBN 3-13-103512-9 .
Web links
NCBI: Cancers . In: Genes and Disease (online book)
This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !