Eva Klein

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Eva and Georg Klein (1979)

Eva Klein (born as Éva Fischer on January 22, 1925 in Budapest ) is a Hungarian-Swedish medical doctor and cancer researcher .

Life

Éva Fischer's childhood was marked by the anti-Semitism of the Hungarian Horthy regime . She grew up in a middle-class family in Budapest, attended school there and began studying medicine at Budapest University . After the German Wehrmacht occupied Hungary in March 1944 , the Eichmann Command and its Hungarian helpers deported over 400,000 Hungarian Jews to the Auschwitz concentration camp . Éva Fischer's family was able to hide in the Budapest University Hospital; Among the helpers was the medical student János Szirmai , who was later honored as Righteous Among the Nations on Eva Klein's initiative .

After the war she studied medicine at the University of Szeged and at the University of Budapest. She married the doctor Georg Klein in 1947 and they emigrated to Sweden that same year. They had three children, and Georg not only never took part in the family work, but also accused her of doing too little for her academic career. She brought her former nanny from Budapest to Stockholm and later hired staff for the children and the household. Eva Klein worked with Torbjörn Caspersson at the Karolinska Institute , passed the state medical examination in Stockholm in 1953 and received her doctorate in biology in 1955. In 1955 she became a lecturer in medical cell research and in 1962 a lecturer in tumor biology at the Karolinska Institute. In 1969 she received a professorship there. Klein was co-editor of the journal Seminars in Cancer Biology . She has published 500 journal articles in the fields of cell research, cancer research, immunology and tumor biology.

In her research, Eva Klein also partly worked with her husband; however, they usually had separate research groups at the Karolinska Institute. Both have made significant contributions in the field of cancer research. Eva Klein made a major contribution to research into natural killer cells . In 1975 she and her husband received the William B. Coley Award . In 1991 she was made the first honorary member of the Israeli Immunological Society. In 1993 she received an honorary doctorate from the University of Nebraska Omaha and in 2003 from Ohio State University , Columbus. Klein was admitted to the Royal Swedish Academy of Sciences in 1987 and to the Hungarian Academy of Sciences in 1993 . In 2013 she became a Fellow of the American Association for Cancer Research .

Klein translated literary works by Dezső Kosztolányi , Attila József , Miklós Radnóti and Sándor Kányádi from Hungarian into Swedish.

Fonts (selection)

  • Transformation of Solid into Ascites Tumors . The Wallenberg laboratory institute for cell research and genetics. Karolinska Institutet, Stockholm. Almquist och Wiksells boktryckeri, Uppsala 1955, OCLC 676909914 (Dissertation University of Stockholm, Karolinska Institute , 1955, 40 pages, 5 supplements).
  • with Georg Klein: Antigenic properties of lymphomas induced by the Moloney agent . 1964.
  • with Georg Klein: How one thing has led to another . 1989, doi: 10.1146 / annurev.iy.07.040189.000245 .
  • with Federico Garrido: The Role of MHC class I and II antigen expression in immune surveillance against tumors. I. Human tumors . (= Seminars in cancer biology. V. 2, no. 1). Saunders, 1991, OCLC 59988656 .
  • with Georg Klein: Bridge or ravine? : ideas that cross the border between scientists and non-scientists do not always survive. In: Nature . Vol. 413, No. 6854, September 2001, p. 365, doi: 10.1038 / 35096653 .
  • with Georg Klein: Foreword for: Imre Kertész : Mannen utan öde . Fiasco; Kaddish för ett ofött barn . Translation Maria Ortman. Norstedt, Stockholm 1998, ISBN 91-7263-915-6 . (Swedish)
  • as editor: Acquired immunodeficiency syndrome (= Progress in Allergy . Volume 37). Karger, Basel 1986, ISBN 3-8055-4156-2 (English).

literature

  • Magdolna Hargittai : Women Scientists: Reflections, Challenges, and Breaking Boundaries . Oxford University Press, 2015, ISBN 978-0-19-935998-1 , pp. 44-48.
  • Shuguang Zhang: Designer self-assembling peptide nanofiber scaffolds for study of 3-D cell Biology and beyond. In: George F. Vande Woude: (Ed.): Advances in Cancer Research. Volume 99, 2008, ISBN 978-0-12-374224-7 , pp. 336-362.

Web links

Individual evidence

  1. Magdolna Hargittai: Women Scientists. 2015, p. 44.
  2. Magdolna Hargittai: Women Scientists. 2015, p. 46.
  3. ^ R. Kiessling, E. Klein, H. Wigzell: "Natural" killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype. In: Eur. J. Immunol. 5, 1975, pp. 112-117.
  4. Imre Kertész: Novel des Fateless (= Nobel Prize Library . Volume 2002). Novel. From the Hungarian original: Sorstalanság , translated by Christina Viragh. Springer, Berlin 2011, ISBN 978-3-942656-35-1 .