Friedrich Weygand

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Friedrich Weygand (born October 1, 1911 in Eichelsdorf , † September 18, 1969 in Munich ) was a German chemist and university professor.

life and work

Weygand studied at the University of Frankfurt from 1930 , completed his dissertation with Richard Johann Kuhn at the Kaiser Wilhelm Institute (KWI) for medical research in Heidelberg and received his doctorate in Frankfurt in 1936 . Then he was Kuhn's assistant in Heidelberg until 1943. In 1938/39 he was on a research stay in Oxford with Robert Robinson . At the time of National Socialism , he joined the SA in 1933 and the NSDAP in 1941 . In 1940 he completed his habilitation and became a private lecturer. From 1943 he was Associate Professor of Organic Chemistry at the University of Strasbourg . After the war he was interned in the USA for a year and a half, from 1946 assistant at the University of Heidelberg and from 1953 associate professor at the University of Tübingen . In 1955 he became a full professor at the Technical University of Berlin and in 1958 a full professor of organic chemistry at the Technical University of Munich .

At Kuhn, Weygand worked on flavin derivatives, the formation of osazones , N - glycosides and the Amadori rearrangement . After the war he turned to biochemistry and studied the purine and pyrimidine metabolism in bacteria using radioactive isotopes . He introduced fluoro- amino acids into peptide chemistry (Weygand test for racemization) and mass spectrometry into the sequence analysis of peptides. The p -methoxybenzyloxycarbonyl residue comes from him as a protective group in peptide synthesis. It is also known for the Weygand aldehyde - synthesis of aromatic aldehydes by reducing carboxylic acid N -methylanilid with lithium aluminum hydride. The Weygand-Löwenfeld breakdown (1950) of sugar oximes with 2,4-dinitrofluorobenzene is named after him and Rudolf Löwenfeld.

He took professional singing lessons. He was a member of the Bavarian Academy of Sciences and the Leopoldina . In 1961 he received the Emil Fischer Medal .

literature

Individual evidence

  1. ^ H. Simon, W. Steglich: Obituary Friedrich Weygand (with list of publications). In: Journal of Nature Research B . 25, 1970, pp. 126-133 ( online ).
  2. ^ Ernst Klee: Das Personenlexikon zum Third Reich , Frankfurt am Main 2007, p. 674.
  3. ^ Louis Fieser, Mary Fieser: Organische Chemie , Verlag Chemie Weinheim, 2nd edition, 1972, p. 1002, ISBN 3-527-25075-1 .
  4. ↑ Friedrich Weygand, Rudolf Löwenfeld: A new sugar mining. In: Chemical Reports. 83, 1950, p. 559, doi : 10.1002 / cber.19500830610 .
personal data
SURNAME Weygand, Friedrich
BRIEF DESCRIPTION German chemist and university professor
DATE OF BIRTH October 1, 1911
PLACE OF BIRTH Eichelsdorf
DATE OF DEATH 18th September 1969
Place of death Munich