Harold Dudley

from Wikipedia, the free encyclopedia

Harold Ward Dudley (born October 30, 1887 in Derby (Derbyshire) , † October 3, 1935 in London ) was an English biochemist.

Dudley studied chemistry at the University of Leeds with a master's degree and received his doctorate in 1912 under Emil Fischer at the University of Berlin . Then he went to the Institute of Christian A. Herter and Henry Drysdale Dakin in New York City , where he discovered the enzyme glyoxalase with Dakin . In 1914 he returned to England and taught biochemistry at the Animal Nutrition Research Institute. After military service in World War I, he went to the Department of Biochemistry and Pharmacology at the National Institute for Medical Research in Hampstead (London) , where he worked under Henry Hallett Daleworked. Initially he worked on oxytocin and vasopressin from the pituitary gland. In 1922 he worked with Frederick Banting and Charles Herbert Best in Toronto and with the Eli Lilly company in Indianapolis to study the state of insulin production. He then developed a process himself that was used industrially in England. With Dale he discovered acetylcholine in the spleen. He also did research on histamine .

With Otto Rosenheim and Walter William Starling, he clarified the structure of spermine .

literature

Individual evidence

  1. Dudley, Rosenheim, Starling, The Chemical Constitution of Spermine, Biochem. J., Volume 20, 1926, pp. 1082-1094, PMC 1251823 (free full text)