Indican
Structural formula | ||||||||||||||||
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General | ||||||||||||||||
Surname | Indican | |||||||||||||||
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Molecular formula | C 14 H 17 NO 6 | |||||||||||||||
Brief description |
colorless solid |
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properties | ||||||||||||||||
Molar mass | 295.29 g mol −1 | |||||||||||||||
Physical state |
firmly |
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solubility |
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safety instructions | ||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
The name Indikan (also: Indican ) designates two similar derivatives of indole .
Occurrence
Plant indican is a glycoside of indoxyl and occurs naturally in some plants known as indigo plants, for example Isatis tinctoria ( woad ) or Indigofera tinctoria .
properties
The indican is a colorless, water-soluble compound that is split by enzymes into ((glucose)) and yellow ((indoxyl)). Oxidation turns indoxyl into the blue dye indigo .
Urinary indican
Urinary indican (also: uroxanthine ) is the potassium salt of indoxylsulfuric acid. The confusion with the plant Indian is based on an early form of medical diagnosis, the so-called urine examination , in which the color of the urine was used for diagnostic purposes. Attention was paid to the sometimes green to blue coloration of the urine, which is now called in extreme cases purple urine bag syndrome (PUBS) and occurs especially in older catheterized women. This is also due to the dye indigo, but it does not come from the plant indican. The German biochemist Felix Hoppe-Seyler discovered the difference between plant indican and urinary indican in 1863 .
literature
- WN Arnold: King George III's urine and indigo blue. In: The Lancet , 347, 1996, pp. 1811-1813. PMID 8667928 .
Individual evidence
- ↑ a b c d data sheet Indoxyl β-D-glucoside, ≥97% from Sigma-Aldrich , accessed on February 7, 2019 ( PDF ).
- ↑ a b c d Entry on Indican. In: Römpp Online . Georg Thieme Verlag, accessed on February 7, 2019.
- ↑ EFJ Hoppe-Seyler: About Indican as a constant urine component. In: Virchows Arch. 27, 1863, pp. 388-393.