Felix Hoppe-Seyler

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Felix Hoppe-Seyler
Tomb of Felix Hoppe-Seyler (cemetery at the Sankt-Georgs-Kirche in Wasserburg on Lake Constance )

Ernst Felix Immanuel Hoppe-Seyler - also called Felix Hoppe for short - (born December 26, 1825 in Freyburg an der Unstrut , †  August 10, 1895 in Wasserburg on Lake Constance ) was a German doctor, chemist and physiological chemist .

Life

Felix Hoppe, son of the superintendent Ernst Hoppe and Friederike Nietzsch, grew up as an orphan with his brother-in-law Georg Seyler , grandson of the theater director Abel Seyler . He was adopted by Seyler in 1864 and took the name Hoppe-Seyler out of gratitude.

Hoppe-Seyler studied medicine from 1846 at the Friedrichs-Universität Halle , the Universität Leipzig , the Friedrich-Wilhelms Universität zu Berlin , the Charles University in Prague and the University of Vienna . On November 15, 1850 he was in Berlin with a thesis on the structure of cartilage and Something about the chondrin to Dr. med. PhD. He then practiced as a doctor and was a doctor at the workhouse from 1852 to 1854, but continued to do physiological-chemical and medical research. In 1854 he became a prosector in Greifswald, where he also completed his habilitation. In 1856 he became an assistant to Rudolf Virchow at the Pathological Institute of the University of Berlin, where he became associate professor in 1860 . In 1858 he married Agnes Franziska Maria Borstein. Hoppe-Seyler was from 1861 professor of applied chemistry at the Eberhard Karls University of Tübingen and from 1872 full professor of physiological chemistry at the Kaiser-Wilhelms-Universität Strasbourg . He died of a stroke in his house in Wasserburg on Lake Constance at the age of 69.

Felix Hoppe-Seyler is one of the founders of physiological chemistry and molecular biology . He discovered the reversible oxidation of the blood pigment, which he was able to isolate through crystallization in 1862 (as his friend Funke had done before), and thus his role in the body as a transporter of oxygen. He named it hemoglobin . 1869 his pupil discovered Friedrich Miescher the nucleic acids as nucleic in Hoppe-Seyler's laboratory in Tübingen.

Hoppe-Seyler founded the Zeitschrift für Physiologische Chemie (also known as Hoppe-Seyler's Zeitschrift für Physiologische Chemie ) in 1877 , which appears today under the title Biological Chemistry .

He had many German and foreign students, including Hans Thierfelder .

The German Association for Clinical Chemistry and Laboratory Medicine awards Hoppe-Seyler the Felix-Hoppe-Seyler Prize for special scientific achievements and merits in the field of clinical chemistry and laboratory medicine .

In 2015, the museum room “ Schlosslabor Tübingen. Tübingen Castle Laboratory ” was opened in the premises of the former kitchen of Hohentübingen Castle from the Museum of the University of Tübingen. Cradle of Biochemistry ”. His main theme is the discovery of hemoglobin at this location by Hoppe-Seyler and the discovery of the nuclein by Miescher.

Fonts

Commemorative plaque attached to the Tübingen laboratory, 1925
  • Manual of physiological and pathological-chemical analysis. 1858.
  • About the behavior of the blood pigment in the spectrum of sunlight. In: Virchow's archive. Volume 23, 1862, pp. 446-449.
  • About the optical and chemical properties of the blood pigment. In: Centralblatt for medical science. 1864, nos. 52 and 53.
  • Physiological chemistry , 4 volumes. 1877-1881.

editor

literature

Web links

Commons : Felix Hoppe-Seyler  - Collection of pictures, videos and audio files

Individual evidence

  1. ↑ Gerlind Büsche-Schmidt: Hoppe-Seyler [...]. 2005, p. 617.
  2. ^ Wilhelm Erman: Directory of the Berlin University Writings 1810–1885. Olms, Hildesheim / New York 1973, p. 314 ( Google Books ).
  3. ↑ Dissertation: De cartilaginum structura et chondrino nonnulla .
  4. ↑ Gerlind Büsche-Schmid: Hoppe-Seyler [...]. 2005, p. 617.
personal data
SURNAME Hoppe-Seyler, Felix
ALTERNATIVE NAMES Hoppe, Ernst Felix Immanuel (full name)
BRIEF DESCRIPTION German doctor, chemist and physiologist
DATE OF BIRTH December 26, 1825
PLACE OF BIRTH Freyburg (Unstrut)
DATE OF DEATH August 10, 1895
Place of death Wasserburg (Lake Constance)