Isorhamnetine

from Wikipedia, the free encyclopedia
Structural formula
Structural formula of isorhamnetin
General
Surname Isorhamnetine
other names
  • 3,5,7-trihydroxy-2- (4-hydroxy-3-methoxyphenyl) chromen-4-one ( IUPAC )
  • 3-methylquercetin
Molecular formula C 16 H 12 O 7
Brief description

beige powder

External identifiers / databases
CAS number 480-19-3
EC number 207-545-5
ECHA InfoCard 100.006.860
PubChem 5281654
ChemSpider 4444973
Wikidata Q416138
properties
Molar mass 316.26 g mol −1
Physical state

firmly

Melting point

200 ° C

solubility
  • partially soluble in water
  • soluble in acetone, methanol, ethyl acetate and DMSO
safety instructions
GHS labeling of hazardous substances
08 - Dangerous to health

Caution

H and P phrases H: 351
P: 281
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Isorhamnetin is a secondary metabolite of plants that belongs to the group of flavonoids .

Occurrence

Broad-leaved cattail ( Typha latifolia )

Glycosides of this substance with varying sugar components can be found in pears , almonds or in various rose apple plants and pipe flowers . Evidence was also given in pollen from pumpkins and corn . In the broad-leaved cattail plant , which is used in Asian folk medicine, the substance was one of the proven compounds. Evidence in the New Zealand plant Carmichaelia proves the worldwide occurrence of this substance.

biosynthesis

Quercetin is methylated by a methyl transferase . The methyl group is supplied by S-adenosyl methionine .

metabolism

After eating the fruit, the substance was detected in the blood plasma. Glycosidases break down the sugar component in the liver and the substance is then excreted in the urine.

Individual evidence

  1. a b c d Isorhamnetin data sheet at Sigma-Aldrich , accessed on February 4, 2019 ( PDF ).
  2. a b Entry Isorhamnetin at enzolifesciences.com, accessed on February 4, 2019.
  3. ^ A b Tod F. Stuessy, Mikio Ono: Evolution and Speciation of Island Plants . Cambridge University Press, 2007, ISBN 0-521-04832-X , pp. 261 ( limited preview in Google Book search).