Jembrana Disease Virus
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Scientific name | ||||||||||||||||||||||
Jembrana disease virus | ||||||||||||||||||||||
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BIV-J | ||||||||||||||||||||||
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The Jembrana Disease Virus (JDV or BIV-J) is a retrovirus that belongs to the genus of lentiviruses and can cause acute illness in Bali cattle ( Bos javanicus ). It is a subtype of the BIV ( Bovine Immunodeficiency Virus ), 74% of the nucleotide sequences match. Although this virus is counted among the lentiviruses, the course of a JDV infection is different from the typical slow course of the disease with lentiviruses: It leads to an acute infection with a sometimes fatal course. This also distinguishes JDV infection from BIV infection.
The Jembrana disease was in 1964 as a disease in cattle in the district of Jembrana in Bali in Indonesia observed. The virus is endemic to some areas of Indonesia . 60,000–80,000 cattle died at Jembrana in Bali.
Symptoms
The sick animals show lethargy , fever , lymphadenopathy and lose weight. The mortality is 17% to 20%.
therapy
No causal therapy is known.
Web links
- Jembrana disease virus (Animal Health Program)
- H. Chen, G. Wilcox et al .: Characterization of the Jembrana Disease Virus tat Gene and the cis- and trans-Regulatory Elements in Its Long Terminal Repeats . Journal of Virology (1999) 73.1: pp. 658-666 [1]
- GE Wilcox, BJ Chadwick and G. Kertayadnya: Recent advances in the understanding of Jembrana disease. Vet. Microbiol. (1995) 46 (1-3): pp. 249-55 PMID 8545963
- Classification of the Jembrana Disease Virus (NCBI Taxonomy)
Individual evidence
- ↑ a b c d ICTV: ICTV Taxonomy history: Commelina yellow mottle virus , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)