James Wilfred Cook

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Sir James Wilfred Cook (born December 10, 1900 in South Kensington , London , † October 21, 1975 in Budleigh Salterton near Exeter ) was a British chemist.

The worker's son studied at 1917 Chemistry at University College London with a Bachelor's degree in 1920. While he taught at a technical school, he received the 1921 master's degree and in 1923 with the theme Some derivatives of anthracene doctorate (Ph. D., and D. Sc. 1925). After a short time at the Chemical Research Laboratory in Teddington he was from 1929 at the Royal Cancer Hospital, where he was lecturer for pathological chemistry in 1932. In 1939 he became Regius Professor of Chemistry at the University of Glasgow and from 1954 until his retirement in 1965 he was Rector of the University of Exeter .

In his retirement from 1966 to 1970 he was involved in the establishment of various universities in Africa (Kampala, where he was Vice Rector, Nigeria, Botswana, Zambia) and advised the newly established New University of Ulster in Northern Ireland.

He showed that the cancer-causing components of the coal - tar polycyclic aromatic hydrocarbons, and developed during the systematic search for carcinogenic substances Bogert Cook Synthesis of phenanthrene (1933). He suspected that steroids were carcinogenic, and the methylcholanthrene he synthesized (1934) was the most potent known carcinogen at the time.

Later he dealt with the investigation of anticancer agents , cytostatics such as colchicine and its derivatives and based on this he investigated other hydrocarbons with rings of 7 carbon atoms ( tropolones , azulene ). He was the first to synthesize tropolone and thujaplicine ( isopropyltropolone ).

In 1954 he received the Davy Medal . In 1938 he became a Fellow of the Royal Society and in 1940 of the Royal Society of Edinburgh .

literature

Individual evidence

  1. Life data, publications and academic family tree of James Wilfred Cook at academictree.org, accessed on January 28, 2018.
  2. ^ The University of Glasgow Story James Wilfred Cook ; from the University of Glasgow website, accessed January 20, 2015.
  3. ^ Fellows Directory. Biographical Index: Former RSE Fellows 1783–2002. Royal Society of Edinburgh, accessed October 18, 2019 .